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AB211062

Human Neuro Antibody Array I (Membrane, 20 Targets)

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Abcam's Human Neuro Antibody Array I (ab211062) for use with cell culture media, serum, plasma, cell and tissue lysates and other liquid samples.

View Alternative Names

Neurotrophic factor BDNF precursor form, proBDNF, Abrineurin, Brain-derived neurotrophic factor, BDNF

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Multiplex Protein Detection - Human Neuro Antibody Array I (Membrane, 20 Targets) (AB211062)
  • Multiplex Protein Detection

Supplier Data

Multiplex Protein Detection - Human Neuro Antibody Array I (Membrane, 20 Targets) (AB211062)

Typical results.

Membranes were probed with conditioned media from two different cell lines. Membranes were exposed to film at room temperature for 1 minute.

Key facts

Reacts with

Human

Target

BDNF

target

Applications

Multiplex Protein Detection

applications

Sample types

Tissue Lysate, Plasma, Cell culture media, Serum, Other biological fluids, Cell Lysate

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "Multiplex Protein Detection": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Abcam's Human Neuro Antibody Array I (ab211062) for use with cell culture media, serum, plasma, cell and tissue lysates and other liquid samples.

Targets: BDNF, beta-NGF, GCSF, GDNF, HB-EGF, IFN gamma, IGF-1, IL-10, IL-1 alpha, IL-1 beta, IL-6, IL-8, MCP-1, MIP-1 alpha, MMP-2, MMP-3, S100B, TGF beta, TNF alpha, VEGF-A.

Cytokine arrays are an antibody-pair-based assay, analogous to ELISA, but using a membrane as a substrate rather than a plate. Capture antibodies are supplied arrayed/spotted on a membrane with each pair of spots representing a different analyte. Sample is added (0.2-1 mL of 1 sample to each membrane), and then paired biotinylated detector antibodies and streptavidin HRP. The cytokine array is analyzed using the same methods as a chemiluminescent western blot. Comparison between samples can be by eye or using densitometry software for a semi-quantitative comparison. "

REACH authorisation
Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances.
It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.

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What's included?

{ "values": { "8Membrane": { "sellingSize": "8 Membrane", "publicAssetCode":"ab211062-8Membrane", "assetComponentDetails": [ { "size":"1 x 1 Unit", "name":"Plastic sheets", "number":"AB211062-CMP02" }, { "size":"2 x 25 mL", "name":"1X Blocking Buffer", "number":"AB211062-CMP01" }, { "size":"1 x 2.5 mL", "name":"Detection Buffer C", "number":"AB211062-CMP04" }, { "size":"1 x 50 µL", "name":"1,000X HRP-Conjugated Streptavidin", "number":"AB211062-CMP03" }, { "size":"1 x 20 mL", "name":"20X Wash Buffer I", "number":"AB211062-CMP06" }, { "size":"4 x 1 Vial", "name":"Biotinylated Antibody Cocktail", "number":"AB211062-CMP09" }, { "size":"4 x 2 Unit", "name":"Antibody Arrays", "number":"AB211062-CMP11" }, { "size":"1 x 20 mL", "name":"20X Wash Buffer II", "number":"AB211062-CMP07" }, { "size":"1 x 2.5 mL", "name":"Detection Buffer D", "number":"AB211062-CMP05" }, { "size":"1 x 16 mL", "name":"2X Cell Lysis Buffer", "number":"AB211062-CMP08" }, { "size":"1 x 1 Unit", "name":"8-Well Incubation Tray (with Lid)", "number":"AB211062-CMP10" } ] }, "4Membrane": { "sellingSize": "4 Membrane", "publicAssetCode":"ab211062-4Membrane", "assetComponentDetails": [ { "size":"2 x 2 Unit", "name":"Antibody Arrays", "number":"AB211062-CMP11" }, { "size":"1 x 50 µL", "name":"1,000X HRP-Conjugated Streptavidin", "number":"AB211062-CMP03" }, { "size":"1 x 10 mL", "name":"20X Wash Buffer I", "number":"AB211062-CMP06" }, { "size":"1 x 1 Unit", "name":"8-Well Incubation Tray (with Lid)", "number":"AB211062-CMP10" }, { "size":"2 x 1 Vial", "name":"Biotinylated Antibody Cocktail", "number":"AB211062-CMP09" }, { "size":"1 x 10 mL", "name":"20X Wash Buffer II", "number":"AB211062-CMP07" }, { "size":"1 x 1.5 mL", "name":"Detection Buffer D", "number":"AB211062-CMP05" }, { "size":"1 x 10 mL", "name":"2X Cell Lysis Buffer", "number":"AB211062-CMP08" }, { "size":"1 x 25 mL", "name":"1X Blocking Buffer", "number":"AB211062-CMP01" }, { "size":"1 x 1 Unit", "name":"Plastic sheets", "number":"AB211062-CMP02" }, { "size":"1 x 1.5 mL", "name":"Detection Buffer C", "number":"AB211062-CMP04" } ] }, "2Membrane": { "sellingSize": "2 Membrane", "publicAssetCode":"ab211062-2Membrane", "assetComponentDetails": [ { "size":"1 x 10 mL", "name":"2X Cell Lysis Buffer", "number":"AB211062-CMP08", "productcode":"" }, { "size":"1 x 1.5 mL", "name":"Detection Buffer D", "number":"AB211062-CMP05", "productcode":"" }, { "size":"1 x 2 Unit", "name":"Antibody Arrays", "number":"AB211062-CMP11", "productcode":"" }, { "size":"1 x 1.5 mL", "name":"Detection Buffer C", "number":"AB211062-CMP04", "productcode":"" }, { "size":"1 x 10 mL", "name":"20X Wash Buffer I", "number":"AB211062-CMP06", "productcode":"" }, { "size":"1 x 25 mL", "name":"1X Blocking Buffer", "number":"AB211062-CMP01", "productcode":"" }, { "size":"1 x 10 mL", "name":"20X Wash Buffer II", "number":"AB211062-CMP07", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Plastic sheets", "number":"AB211062-CMP02", "productcode":"" }, { "size":"1 x 1 Unit", "name":"8-Well Incubation Tray (with Lid)", "number":"AB211062-CMP10", "productcode":"" }, { "size":"1 x 1 Vial", "name":"Biotinylated Antibody Cocktail", "number":"AB211062-CMP09", "productcode":"" }, { "size":"1 x 50 µL", "name":"1,000X HRP-Conjugated Streptavidin", "number":"AB211062-CMP03", "productcode":"" } ] } } }
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
-20°C
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Product protocols

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Target data

The protein expressed by the BDNF gene is a critical signaling molecule that activates pathways downstream of NTRK2, as well as the heterodimeric receptor formed by NGFR and SORCS2. During development, it aids the survival and differentiation of specific neuronal populations in both the peripheral and central nervous systems. It is involved in axonal growth, pathfinding, and modulation of dendritic growth and morphology. In adult synapses, BDNF is a key regulator of synaptic transmission and plasticity in various CNS regions, contributing to processes like long-term potentiation, long-term depression, some short-term synaptic plasticity forms, and the homeostatic regulation of intrinsic neuronal excitability. Signaling through NGFR and SORCS2 is linked to synaptic plasticity and long-term depression, while its binding to these receptors also promotes neuronal apoptosis. This supplementary information is collated from multiple sources and compiled automatically.
See full target information BDNF

Additional targets

NGF,CSF3,GDNF,HBEGF,IFNG,IGF1,IL1A,IL1B,IL10,IL6,CXCL8,CCL2,CCL3,MMP2,MMP3,S100B,TGFB1,TNF,VEGFA
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websiteProtocolBooklet
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Product promise

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For full details, please see our Terms & Conditions

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