Covid-19 GeoMx-formatted Antibody Panel ab273594 is designed for use with NanoString Digital Spatial Profiling (DSP) technology.
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- Cell reports. Medicine 3:1005222022System-wide transcriptome damage and tissue identity loss in COVID-19 patients.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJiwoon Park,Jonathan Foox,Tyler Hether,David C Danko,Sarah Warren,Youngmi Kim,Jason Reeves,Daniel J Butler,Christopher Mozsary,Joel Rosiene,Alon Shaiber,Evan E Afshin,Matthew MacKay,André F Rendeiro,Yaron Bram,Vasuretha Chandar,Heather Geiger,Arryn Craney,Priya Velu,Ari M Melnick,Iman Hajirasouliha,Afshin Beheshti,Deanne Taylor,Amanda Saravia-Butler,Urminder Singh,Eve Syrkin Wurtele,Jonathan Schisler,Samantha Fennessey,André Corvelo,Michael C Zody,Soren Germer,Steven Salvatore,Shawn Levy,Shixiu Wu,Nicholas P Tatonetti,Sagi Shapira,Mirella Salvatore,Lars F Westblade,Melissa Cushing,Hanna Rennert,Alison J Kriegel,Olivier Elemento,Marcin Imielinski,Charles M Rice,Alain C Borczuk,Cem Meydan,Robert E Schwartz,Christopher E MasonPubMed 35233546
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Covid-19 GeoMx-formatted Antibody Panel ab273594 is designed for use with NanoString Digital Spatial Profiling (DSP) technology.
Storage
- Shipped at conditions
- Dry Ice
- Appropriate long-term storage conditions
- -80°C
- Storage information
- -80°C
Notes
Covid-19 GeoMx-formatted Antibody Panel ab273594 is designed for use with NanoString Digital Spatial Profiling (DSP) technology. To use this panel you must also purchase Covid-19 GeoMx-formatted Panel Probe R Mix ab273595 and also a Core GeoMx antibody panel from Nanostring. Please also contact us (NanostringRequests@abcam.com) to request the bioinformatics file required to use this panel in your GeoMx Assay.
This antibody panel is supplied as one pre-mixed vial containing 112 µl of antibody mix sufficient for 12 slides:
- Recombinant Anti-ACE2 antibody HLA-DPB1 antibody [EPR4436] conjugated to GeoMx tag ID0314
- Recombinant Anti-TMPRSS2 antibody [EPR3861] conjugated to GeoMx tag ID0315
- Recombinant Anti-Cathepsin L/V/K/H antibody [EPR8011] conjugated to GeoMx tag ID0321
- Recombinant Anti-DDX5 antibody [EPR7239] conjugated to GeoMx tag ID0322
- Anti-SARS-cov2 Spike antibody ab272504 conjugated to GeoMx tag ID0318NB ab272504 is a polyclonal antibody
Use this panel as a GeoMx Custom Module as explained in the GeoMx DSP Slide Preparation User Manual from NanoString (www.nanostring.com/geomx-online-user-manual). You can use this module as you would other GeoMx Modules and do not need to follow the instructions specific to custom antibody spike-ins.
Up to 5 GeoMx-formatted antibodies from Abcam can be combined into one panel for use in a GeoMx DSP Assay. This panel contains 5 antibodies so it cannot be combined with other GeoMx-formatted antibodies from Abcam. Please contact us if you would like to purchase the antibodies contained within this panel as individual GeoMx-formatted antibodies.
This panel can be combined with GeoMx Assay panels purchased from Nanostring. For a full list of pre-validated NanoString GeoMx Assays, visit www.nanostring.com/products/geomx-digital-spatial-profiler/geomx-assays
To learn more about Abcam’s GeoMx-formatted antibodies and custom conjugation services, please visit here.
To learn more about NanoString's Covid19 products, please visit www.nanostring.com/COVID19
NanoString, nCounter and GeoMx are trademarks or registered trademarks of NanoString Technologies, Inc., in the United States and/or other countries.
Product promise
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Covid-19 GeoMx-formatted Antibody Panel (ab273594)
GeoMx-formatted TMPRSS2 antibody clone EPR3861, ACE2 antibody clone EPR4436, Cathepsin L/V/K/H antibody clone EPR8011, and DDX5 antibody clone EPR7239 tested in conventional IHC in human formalin-fixed paraffin embedded tissue sections to confirm that antibody specificity is retained after oligo-conjugation.
GeoMx-formatted SARS-COV-2 spike glycoprotein antibody tested in SARS-COV-2 spike glycoprotein overexpressing HEK293 cell line slides to confirm that antibody specificity is retained after oligo-conjugation.
The same staining pattern was seen in the conjugated antibody as with the unconjugated control antibody (unconjugated antibody data not shown).
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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