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Neural Progenitor Cell Marker (CXCR4, Nestin, PDGFR, SOX2, Vimentin, Doublecortin) Antibody Panel (ab263461) is part of the multiplex kits range. Abcam offers high-quality biological reagents and tools including antibodies, proteins, assays, cell lines and lysates.

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Images

Immunocytochemistry/ Immunofluorescence - Neural Progenitor Cell Marker (CXCR4, Nestin, PDGFR, SOX2, Vimentin, Doublecortin) Antibody Panel (AB263461), expandable thumbnail
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Neural Progenitor Cell Marker (CXCR4, Nestin, PDGFR, SOX2, Vimentin, Doublecortin) Antibody Panel (AB263461), expandable thumbnail
  • Immunocytochemistry/ Immunofluorescence - Neural Progenitor Cell Marker (CXCR4, Nestin, PDGFR, SOX2, Vimentin, Doublecortin) Antibody Panel (AB263461), expandable thumbnail
  • Immunocytochemistry/ Immunofluorescence - Neural Progenitor Cell Marker (CXCR4, Nestin, PDGFR, SOX2, Vimentin, Doublecortin) Antibody Panel (AB263461), expandable thumbnail
  • Immunocytochemistry/ Immunofluorescence - Neural Progenitor Cell Marker (CXCR4, Nestin, PDGFR, SOX2, Vimentin, Doublecortin) Antibody Panel (AB263461), expandable thumbnail

Key facts

Reactive species
Human
Target
CXCR4
(See target data below)

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Target data

Function

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation (PubMed:10452968, PubMed:18799424, PubMed:24912431, PubMed:28978524). Involved in the AKT signaling cascade (PubMed:24912431). Plays a role in regulation of cell migration, e.g. during wound healing (PubMed:28978524). Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels (PubMed:20228059). Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (PubMed:11276205). Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival (By similarity). (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) for human immunodeficiency virus-1/HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus (PubMed:10074122, PubMed:10756055, PubMed:8849450, PubMed:8929542, PubMed:9427609).

Additional Targets

NES, PDGFRA phospho Y572 + Y574, SOX2, VIM, DCX

Alternative names

Recommended products

Neural Progenitor Cell Marker (CXCR4, Nestin, PDGFR, SOX2, Vimentin, Doublecortin) Antibody Panel (ab263461) is part of the multiplex kits range. Abcam offers high-quality biological reagents and tools including antibodies, proteins, assays, cell lines and lysates.

Key facts

Reactive species
Human
Target
CXCR4

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
-20°C

Notes

Neural Progenitor Cell Marker (CXCR4, Nestin, PDGFR, SOX2, Vimentin, Doublecortin) Antibody Panel ab263461 contains multiple trial-sized versions of anti-human antibody clones against CXCR4, Nestin, PDGFR, SOX2, Vimentin, Doublecortin, specifically selected for high performance in various applications. This panel contains 6 recombinant rabbit monoclonal antibodies against human CXCR4, Nestin, PDGFR, SOX2, Vimentin, Doublecortin. They are provided as a sampler panel to allow you to easily evaluate each antibody.

For guidelines on how to use each antibody within the panel, please consult the individual datasheet for each antibody.

Panel contains:

- Rabbit monoclonal [UMB2] to CXCR4 (20 μL) ab124824

- Rabbit monoclonal [SP103] to Nestin (20 μL) ab105389

- Rabbit monoclonal [EPR22059-270] to PDGFR alpha (20 μL) ab203491

- Rabbit monoclonal [EPR3131] to SOX2 (20 μL) ab92494

- Rabbit monoclonal [EPR3776] to Vimentin - Cytoskeleton Marker (20 μL) ab92547

- Rabbit monoclonal [EPR19997] to Doublecortin (20 μL) ab207175


Explore our range of antibody sample panels designed to provide you with a variety of trial-size antibodies in a convenient and cost-effective format.

Carrier-free formulations of our recombinant antibodies are also available for easy conjugation to labels of your choice and for multiplex applications. Use our intuitive search and select carrier-free or your label of choice. For bespoke conjugations or large volumes email bespoke@abcam.com.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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