The ?-Glucosidase Inhibitor Screening Kit (ab284520) (K938) can be used to screen potential inhibitors of this enzyme.
Individual kit components also available for purchase with a minimum order of 20 units. Contact us to discuss your needs.
Colorimetric
Inhibitor compounds
Enzyme activity (quantitative)
Essential for the degradation of glycogen in lysosomes (PubMed:1856189, PubMed:7717400, PubMed:14695532, PubMed:18429042). Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans (PubMed:29061980).
Lysosomal alpha-glucosidase, Acid maltase, Aglucosidase alfa, GAA
The ?-Glucosidase Inhibitor Screening Kit (ab284520) (K938) can be used to screen potential inhibitors of this enzyme.
Individual kit components also available for purchase with a minimum order of 20 units. Contact us to discuss your needs.
Lysosomal alpha-glucosidase, Acid maltase, Aglucosidase alfa, GAA
Colorimetric
Inhibitor compounds
Enzyme activity (quantitative)
Microplate (12 x 8 well strips)
Blue Ice
-20°C
-20°C
-20°C
The α-Glucosidase Inhibitor Screening Kit (ab284520) (K938) can be used to screen potential inhibitors of this enzyme. It utilizes the ability of an active α-Glucosidase to cleave a synthetic substrate thus, releasing a chromophore (OD: 410 nm). In the presence of an α-Glucosidase specific inhibitor, the enzymatic activity is greatly reduced which is detected by a decrease of absorbance readings.
The assay kit provides a rapid, simple and reliable test for high-throughput screening of α-Glucosidase inhibitors.
This product is manufactured by BioVision, an Abcam company and was previously called K938 a-Glucosidase Inhibitor Screening Kit (Colorimetric). K938-100 is the same size as the 100 test size of ab284520.
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Terms & Conditions.
Inhibition of alpa-Glucosidase activity by Acarbose.
α-Glucosidase activity inhibition by Acarbose. IC50 of Acarbose was calculated to be 0.74 ± 0.15 mM. Assay was carried out following the kit protocol.
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