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AB102480

Apoptosis Inducer Kit (Ready-to-use)

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(5 Publications)

Apoptosis Inducer Kit (ab102480) contains 5 ready-to-use chemical reagents that induce apoptosis through different mechanisms.

Key facts

Sample types

Suspension cells, Adherent cells

Assay type

Direct

Product details

Apoptosis Inducer Kit (ab102480) contains 5 ready-to-use chemical reagents that induce apoptosis through different mechanisms. Actinomycin D, an antineoplastic antibiotic, inhibits RNA synthesis. Camptothecin, an inhibitor of nuclear topoisomerase, induces apoptosis in many types of cells. Cycloheximide, an active antibiotic against many yeast and fungi, inhibits protein synthesis. Dexamethasone, an active and highly stable glucocorticoid, probably induces apoptosis by binding and activating the intracellular glucocorticoid receptor. Etoposide, a derivative of podophyllotoxin, inhibits topoisomerase activity.

Visit our FAQs page for tips and troubleshooting.

This product is manufactured by BioVision, an Abcam company and was previously called K121 Ready-to-use Apoptosis Inducer Set. K121-5 is the same size as the 5 test size of ab102480.

What's included?

{ "values": { "5Test": { "sellingSize": "5 Test", "publicAssetCode":"ab102480-5Test", "assetComponentDetails": [ { "size":"1 x 100 µL", "name":"Etoposide", "number":"AB102480-CMP02", "productcode":"" }, { "size":"1 x 1 mL", "name":"Camptothecin", "number":"AB102480-CMP05", "productcode":"" }, { "size":"1 x 50 µL", "name":"Actinomycin D", "number":"AB102480-CMP01", "productcode":"" }, { "size":"1 x 1 mL", "name":"Cycloheximide", "number":"AB102480-CMP03", "productcode":"" }, { "size":"1 x 1 mL", "name":"Dexamethasone", "number":"AB102480-CMP04", "productcode":"" } ] } } }

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
-20°C

Product protocols

Target data

See full target information Dactinomycin

Additional targets

Camptothecin,Cycloheximide,Dexamethasone

Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Cell death and differentiation 29:1423-1432 PubMed35017647

2022

Externalized phosphatidylinositides on apoptotic cells are eat-me signals recognized by CD14.

Applications

Unspecified application

Species

Unspecified reactive species

Ok-Hee Kim,Geun-Hyung Kang,June Hur,Jinwook Lee,YunJae Jung,In-Sun Hong,Hookeun Lee,Seung-Yong Seo,Dae Ho Lee,Cheol Soon Lee,In-Kyu Lee,Susan Bonner-Weir,Jongsoon Lee,Young Joo Park,Hyeonjin Kim,Steven E Shoelson,Byung-Chul Oh

Microbial pathogenesis 147:104406 PubMed32738284

2020

Apoptotic blebs from Leishmania major-infected macrophages as a new approach for cutaneous leishmaniasis vaccination.

Applications

Unspecified application

Species

Unspecified reactive species

Roghiyeh Faridnia,Hamed Kalani,Hajar Ziaei Hezarjaribi,Paul W Denny,Alireza Rafie,Mahdi Fakhar,Stela Virgilio

Arteriosclerosis, thrombosis, and vascular biology 38:2562-2575 PubMed30354245

2018

Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation.

Applications

Unspecified application

Species

Unspecified reactive species

Petteri Rinne,Raquel Guillamat-Prats,Martina Rami,Laura Bindila,Larisa Ring,Leo-Pekka Lyytikäinen,Emma Raitoharju,Niku Oksala,Terho Lehtimäki,Christian Weber,Emiel P C van der Vorst,Sabine Steffens

Nature 546:426-430 PubMed28607489

2017

The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival.

Applications

Unspecified application

Species

Unspecified reactive species

Haizhen Wang,Brandon N Nicolay,Joel M Chick,Xueliang Gao,Yan Geng,Hong Ren,Hui Gao,Guizhi Yang,Juliet A Williams,Jan M Suski,Mark A Keibler,Ewa Sicinska,Ulrike Gerdemann,W Nicholas Haining,Thomas M Roberts,Kornelia Polyak,Steven P Gygi,Nicholas J Dyson,Piotr Sicinski

BMB reports 50:43-48 PubMed27866511

2016

Impaired phagocytosis of apoptotic cells causes accumulation of bone marrow-derived macrophages in aged mice.

Applications

FuncS

Species

Unspecified reactive species

Ok-Hee Kim,Hyojung Kim,Jinku Kang,Dongki Yang,Yu-Hoi Kang,Dae Ho Lee,Gi Jeong Cheon,Sang Chul Park,Byung-Chul Oh
View all publications

Product promise

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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