Cortical Astrocytes - Human iPSC derived cells (Male, WC-30)

Product details

These products are extremely sensitive and require specific conditions to maintain cell health and functionality. Please refer to the recommended protocols for the correct methodology in plating and maintaining these cells.

For even greater physiological relevance, co-culture protocols are available for use with Cortical neurons. Co-culture with Cortical astrocytes can be performed with Cortical Glutamatergic Neurons (ab315366), Cortical GABAergic Neurons (ab315368), or a combination of both in varying ratios.

Human Cortical Astrocytes are derived from normal control iPSC line WC-30. BrainXell Human Cortical Astrocytes express key astrocyte markers GFAP and S100β at >70% and exhibit mature process-bearing morphologies as demonstrated by ICC labelling. Cortical Astrocytes uptake glutamate and exhibit calcium waves. Co-culturing the cortical astrocytes with neurons can enhance and accelerate certain aspects of neuronal activity, including network bursts, as demonstrated by multi-electrode array (MEA).

Vials of Cortical Astrocytes are delivered with two supplements which are designed to facilitate the maturation and health of the cultures. BrainFast Astro is a seeding supplement which promotes cell survival at thaw and completes the differentiation process to astrocytes. BrainFast SK enhances the purity of the culture.

In partnership with BrainXell