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AB113468

DNMT Activity Assay Kit (Fluorometric)

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(1 Publication)

DNMT (DNA methylases) is a family of enzymes responsible for the addition of methyl groups on the cytosine ring at the 5' position of a CpG dinucleotide.
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Functional Studies - DNMT Activity Assay Kit (Fluorometric) (AB113468)
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Supplier Data

Functional Studies - DNMT Activity Assay Kit (Fluorometric) (AB113468)

Demonstration of high sensitivity and specificity achieved by using recombinant DNMT1 with ab113468.

Key facts

Detection method

Fluorescent

Assay type

Enzyme activity

Assay time

3h 45m

Assay Platform

Microplate reader

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "Enzyme activity assay": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Product details

DNMT (DNA methylases) is a family of enzymes responsible for the addition of methyl groups on the cytosine ring at the 5' position of a CpG dinucleotide. The DNMT family is required for the establishment and maintenance of DNA methylation patterns.
DNMT Activity Quantification Kit (Fluorometric) (ab113468) allows the user to fluorometrically measure DNA methyltransferase activity or inhibition at extremely fast speed on a 96-stripwell microplate. The kit is ready-to-use and provides all the essential components needed to carry out a successful DNMT activity/inhibition experiment without the need for radioactivity or any special equipment.

What's included?

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
Multi
Appropriate long-term storage conditions
Multi
Storage information
Please refer to protocols

Product protocols

Target data

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature structural & molecular biology 25:951-957 PubMed30275516

2018

DNA G-quadruplex structures mold the DNA methylome.

Applications

Unspecified application

Species

Unspecified reactive species

Shi-Qing Mao,Avazeh T Ghanbarian,Jochen Spiegel,Sergio Martínez Cuesta,Dario Beraldi,Marco Di Antonio,Giovanni Marsico,Robert Hänsel-Hertsch,David Tannahill,Shankar Balasubramanian
View all publications
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