AB113452
Histone H3 (K4) Methyltransferase Activity Quantification Assay Kit
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(1 Publication)
Methylation of histone H3 at lysine 4 (K4) is thought to be a global epigenetic mark in euchromatin and a mediator of activated transcription.
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Supplier Data
Functional Studies - Histone H3 (K4) Methyltransferase Activity Quantification Assay Kit (AB113452)
Nuclear extracts were prepared from MCF-7 cells using the ab113474 and H3-K4 specific histone methyltrasferase activity (SET7/9) was measured.
Reactivity data
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Product details
Methylation of histone H3 at lysine 4 (K4) is thought to be a global epigenetic mark in euchromatin and a mediator of activated transcription. In mammalian cells, several SET-domain containing histone lysine methyltransferases such as MLL1 are responsible for adding one, two or three methyl groups at lysine 4 of histone H3.
Histone H3 (K4) Methyltransferase Activity Quantification Assay Kit (ab113452) allows the user to measure the activity or inhibition of individual histone methyltransferases that specifically target histone H3 at lysine 4 (H3K4). The kit is ready-to-use and provides all the essential components needed to carry out a successful histone methyltransferase activity/inhibition quantification assay without the need for radioactivity or any special equipment.
Histone H3 (K4) Methyltransferase Activity Quantification Assay Kit (ab113452) allows the user to measure the activity or inhibition of individual histone methyltransferases that specifically target histone H3 at lysine 4 (H3K4). The kit is ready-to-use and provides all the essential components needed to carry out a successful histone methyltransferase activity/inhibition quantification assay without the need for radioactivity or any special equipment.
What's included?
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Properties and storage information
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
Multi
Appropriate long-term storage conditions
Multi
Storage information
Please refer to protocols
Product protocols
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Publications (1)
Recent publications for all applications. Explore the full list and refine your search
Diabetes 71:1170-1181 PubMed35290440
2022
Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High-Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation.
Applications
Unspecified application
Species
Unspecified reactive species
Joji Kusuyama,Nathan S Makarewicz,Brent G Albertson,Ana Barbara Alves-Wagner,Royce H Conlin,Noah B Prince,Christiano R R Alves,Krithika Ramachandran,Chisayo Kozuka,Yang Xiudong,Yang Xia,Michael F Hirshman,Toshihisa Hatta,Ryoichi Nagatomi,Eva S Nozik,Laurie J Goodyear
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