Tyrosine Assay Kit (Colorimetric)
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(5 Publications)
Tyrosine Assay Kit (Colorimetric) ab185435 is a simple, yet sensitive assay that is able to detect normal and abnormal concentrations of Tyrosine in biological fluids.
Individual kit components also available for purchase with a minimum order of 20 units. Contact us to discuss your needs.
View Alternative Names
2 amino 3(4 hydroxyphenyl) propanoic acid, 4 hydroxyphenylalanine
- FuncS
Supplier Data
Functional Studies - Tyrosine Assay Kit (Colorimetric) (AB185435)
Tyrosine Standard Curve
- FuncS
Supplier Data
Functional Studies - Tyrosine Assay Kit (Colorimetric) (AB185435)
Measurement of Tyrosine concentration in Human urine and serum.
Both 135 μL samples were deproteinized using 10 kDa Spin Column and spiked with known amount of Tyrosine (30 nmol).
Product details
Tyrosine Assay Kit (Colorimetric) (ab185435) is a simple, yet sensitive assay that is able to detect normal and abnormal concentrations of Tyrosine in biological fluids. The assay is based on the enzymatic oxidation of Tyrosine producing a stable signal (OD 492 nm), which is directly proportional to the amount of Tyrosine. Sample preparation is minimal and does not require strenuous or complicated procedures. The assay can detect as low as 50 uM of Tyrosine in a variety of biological samples.
Other Notes
This product was previously called K573 Biovision Tyrosine Colorimetric Assay Kit. Biovision was acquired by Abcam in 2021.
Tyrosine (Tyr) is one of the four standard amino acids containing an aromatic group as a side chain. Its hydrophobicity is one of the main characteristics of this uncharged polar amino acid. In addition to being an essential amino acid Tyr is important in number of biological processes such as the synthesis of neurotransmitters, thyroid hormones, melanine, fumarate and acetoacetate. The pathology of abnormal concentrations of Tyr is well known in diseases including phenylketonuria, hypothyroidism, tyrosinemia, albinism, and alkaptonuria.
REACH authorisation
Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances.
It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.
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Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Tyrosine functions in protein synthesis as one of the 20 standard amino acids. It incorporates into proteins through ribosomal translation. Tyrosine is part of the large multi-enzyme complex involved in melanin production impacting pigmentation in skin and hair. This incorporation and synthesis contribute to tyrosine's varied biological roles including enzyme regulation.
Pathways
Tyrosine plays critical roles in several metabolic and signaling pathways. The catecholamine biosynthesis pathway utilizes tyrosine to synthesize neurotransmitters important for nervous system functions. Tyrosine kinase signaling pathways rely on tyrosine residues that undergo phosphorylation facilitating signal transduction for cellular processes. Proteins such as the insulin receptor and epidermal growth factor receptor are closely connected in these pathways.
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Publications (5)
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Nature communications 15:8971 PubMed39420002
2024
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Insects 15: PubMed38249041
2024
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International journal of molecular sciences 21: PubMed33260674
2020
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Nature communications 10:4266 PubMed31537781
2019
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Advanced pharmaceutical bulletin 9:331-334 PubMed31380262
2019
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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