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AB245888

Wright-Giemsa Stain Kit

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(10 Publications)

Wright-Giemsa Stain Kit ab245888 is used for differential staining of blood smears, bone marrow and blood parasites.
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Staining - Wright-Giemsa Stain Kit (AB245888)
  • Staining

Supplier Data

Staining - Wright-Giemsa Stain Kit (AB245888)

Staining using ab245888 Wright-Giemsa Stain Kit.

Key facts

Sample types

Tissue sections

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Product details

Wright-Giemsa Stain Kit ab245888 is intended to be used for differential staining of blood smears, bone marrow and blood parasites. Erythrocytes: Pink-Tan Leukocytes: Blue-Purple Neutrophils: Light Purple or Lavender granules in cytoplasm. Eosinophils: Bright Red or Red-Orange granules in cytoplasm. Basophils: Deep Purple or Violet-Black granules in cytoplasm. Platelets: Violet-Purple granules in light blue cytoplasm. **Control Tissue:** Blood smear on clean slide. **Other products for staining tissue sections** Find more kits and reagents in the , or products for antigen retrieval, blocking, signal amplification, visualization, counterstaining, and mounting in the .
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What's included?

{ "values": { "1Kit": { "sellingSize": "1 Kit", "publicAssetCode":"ab245888-1Kit", "assetComponentDetails": [ { "size":"1 x 500 mL", "name":"Wright-Giemsa Solution", "number":"AB245888-CMP02", "productcode":"" }, { "size":"2 x 500 mL", "name":"Phosphate Buffer Solution (pH 6.8)", "number":"AB245888-CMP01", "productcode":"" } ] } } }
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Ambient
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Wright-Giemsa staining also known as Giemsa stain or Wright stain serves an important role in the differentiation and identification of blood cells. This staining method involves dyes like eosin and methylene blue which bind to different cell components. It distinguishes between different types of white blood cells red blood cells and platelets by making use of the unique characteristics of cellular components. It has widespread application in hematological studies due to its ability to provide detailed visualization of cellular morphology. This stain is expressed broadly across laboratories for blood smear analysis.
Biological function summary

The staining technique assists in identifying and discriminating cell types within blood samples. Wright-Giemsa staining reveals the presence and morphology of cells assisting researchers in examining the granular content and cytoplasmic details of leukocytes. It specifically highlights mitochondrial components and nucleic structures within cells forming a complex with these cell structures to enhance visibility under a microscope. The eosin and methylene blue components produce color variations that allow for the examination of different cellular features.

Pathways

Wright-Giemsa staining intersects notably with blood cell differentiation pathways and anemia-related investigations. It aids in exploring hematopoiesis by revealing the presence and developmental stages of blood cells. By differentiating cell populations this staining supports the identification of various stages within blood formation pathways including those involving proteins like erythropoietin and hematopoietic growth factors. Such interactions allow insight into cellular development and immune responses through visible morphology changes.

The Wright-Giemsa stain finds critical application in diagnosing leukemia and malaria. It enables the identification of abnormal white blood cell populations which can indicate leukemic conditions by highlighting morphological abnormalities. Additionally it helps in detecting Plasmodium species in malaria by bringing out the distinctive ring forms in red blood cells. The staining provides an effective tool for diagnosing these conditions linking to proteins like histidine-rich protein II in malaria which is useful in clinical settings for diagnosis and monitoring of disease progression.
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Product protocols

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Target data

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Publications (10)

Recent publications for all applications. Explore the full list and refine your search

Clinical and translational medicine 14:e1744 PubMed39166890

2024

Cyclic-di-GMP induces inflammation and acute lung injury through direct binding to MD2.

Applications

Unspecified application

Species

Unspecified reactive species

Chenchen Qian,Weiwei Zhu,Jiong Wang,Zhe Wang,Weiyang Tang,Xin Liu,Bo Jin,Yong Xu,Yuyang Zhang,Guang Liang,Yi Wang

Nature cancer 5:283-298 PubMed38195933

2024

Autotaxin-lysolipid signaling suppresses a CCL11-eosinophil axis to promote pancreatic cancer progression.

Applications

Unspecified application

Species

Unspecified reactive species

Sohinee Bhattacharyya,Chet Oon,Luis Diaz,Holly Sandborg,Erin S Stempinski,Michelle Saoi,Terry K Morgan,Claudia S López,Justin R Cross,Mara H Sherman

Cellular & molecular biology letters 28:91 PubMed37946128

2023

Irf7 regulates the expression of Srg3 and ferroptosis axis aggravated sepsis-induced acute lung injury.

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Unspecified application

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Unspecified reactive species

Xinyu Ling,Shiyou Wei,Dandan Ling,Siqi Cao,Rui Chang,Qiuyun Wang,Zhize Yuan

Biomaterials 301:122267 PubMed37633022

2023

Modeling and countering the effects of cosmic radiation using bioengineered human tissues.

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Unspecified application

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Unspecified reactive species

Daniel Naveed Tavakol,Trevor R Nash,Youngbin Kim,Siyu He,Sharon Fleischer,Pamela L Graney,Jessie A Brown,Martin Liberman,Manuel Tamargo,Andrew Harken,Adolfo A Ferrando,Sally Amundson,Guy Garty,Elham Azizi,Kam W Leong,David J Brenner,Gordana Vunjak-Novakovic

NPJ Regenerative medicine 8:46 PubMed37626061

2023

Ferric citrate and apo-transferrin enable erythroblast maturation with β-globin from hemogenic endothelium.

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Unspecified reactive species

Soo-Been Jeon,Hyebin Koh,A-Reum Han,Jieun Kim,Sunghun Lee,Jae-Ho Lee,Seung-Soon Im,Young-Sup Yoon,Jong-Hee Lee,Ji Yoon Lee

Nature metabolism 5:1188-1203 PubMed37414931

2023

Human resident liver myeloid cells protect against metabolic stress in obesity.

Applications

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Unspecified reactive species

Emelie Barreby,Benedikt Strunz,Sebastian Nock,Léa Naudet,Joanne X Shen,Helene Johansson,Isabella Sönnerborg,Junjie Ma,Egon Urgard,Laura J Pallett,Yizhou Hu,Achilleas Fardellas,Valerio Azzimato,Ana Vankova,Laura Levi,Cecilia Morgantini,Mala K Maini,Per Stål,Stephan P Rosshart,Jonathan M Coquet,Greg Nowak,Erik Näslund,Volker M Lauschke,Ewa Ellis,Niklas K Björkström,Ping Chen,Myriam Aouadi

Journal of inflammation (London, England) 20:13 PubMed37024954

2023

Efficacy of CU06-1004 via regulation of inflammation and endothelial permeability in LPS-induced acute lung injury.

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Unspecified reactive species

Yeomyeong Kim,Cho-Rong Bae,Dongyeop Kim,Hyejeong Kim,Sunghye Lee,Haiying Zhang,Minyoung Noh,Young-Myeong Kim,Naoki Mochizuki,Young-Guen Kwon

Cell proliferation 56:e13366 PubMed36478274

2022

CD34 cells identified as pluripotent stem cell-derived definitive hemogenic endothelium purified using bone morphogenetic protein 4.

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Unspecified application

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Unspecified reactive species

Soo-Been Jeon,A-Reum Han,Sunghun Lee,Seung Chan Lee,Min Ji Lee,Soon-Jung Park,Sung-Hwan Moon,Ji Yoon Lee

International journal of stem cells 16:108-116 PubMed36310028

2022

Lymphoid Lineage γδ T Cells Were Successfully Generated from Human Pluripotent Stem Cells via Hemogenic Endothelium.

Applications

Unspecified application

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Unspecified reactive species

Soo-Been Jeon,A-Reum Han,Yoo Bin Choi,Ah Reum Lee,Ji Yoon Lee

Aging 13:18423-18441 PubMed34315133

2021

Yiqi Jiemin decoction alleviates allergic rhinitis in a guinea pig model by suppressing inflammation, restoring Th1/Th2 balance, and improving cellular metabolism.

Applications

Unspecified application

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Unspecified reactive species

Zhanfeng Yan,Lili Liu,Jingjing Yuan,Lulu Jiao,Mo Zhou,Jinfeng Liu,Xiaohui Wen,Siming Liu,Pengpeng Hao,Jianhua Liu,Wei Wu
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