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AB275320

1-Methylguanine

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(3 Publications)

MW 165.15 Da. Naturally occurring modified purine derived from tRNA, found in elevated levels in the serum and urine of cancer patients. (PMID: 2413515).
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Chemical Structure - 1-Methylguanine (AB275320)
  • Chemical Structure

Lab

Chemical Structure - 1-Methylguanine (AB275320)

Chemical structure of 1-Methylguanine, 938-85-2

Key facts

CAS number

938-85-2

Form

Solid

form

Molecular weight

165.15 Da

Molecular formula

C<sub>6</sub>H<sub>7</sub>N<sub>5</sub>O

PubChem

70315

Nature

Synthetic

Solubility

Soluble in DMSO

Biochemical name

1-Methylguanine

Biological description

Naturally occurring modified purine derived from tRNA, found in elevated levels in the serum and urine of cancer patients. (PMID: 2413515).

Canonical smiles

CN1C(=O)C2=C(N=CN2)N=C1N

InChi

InChI=1S/C6H7N5O/c1-11-5(12)3-4(9-2-8-3)10-6(11)7/h2H,1H3,(H2,7,10)(H,8,9)

InChiKey

RFLVMTUMFYRZCB-UHFFFAOYSA-N

IUPAC Name

2-amino-1-methyl-7H-purin-6-one

Excitation/Emission

Ex: 492nm, Em: 521nm

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions
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Product protocols

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Publications (3)

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Nucleic acids research 32:6260-7 PubMed15576352

2004

Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Pål Ø Falnes

Proceedings of the National Academy of Sciences of 101:14051-6 PubMed15381779

2004

Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli.

Applications

Unspecified application

Species

Unspecified reactive species

James C Delaney,John M Essigmann

The Biochemical journal 318 ( Pt 1):21-3 PubMed8761446

1996

Measurement of oxidized and methylated DNA bases by HPLC with electrochemical detection.

Applications

Unspecified application

Species

Unspecified reactive species

H Kaur,B Halliwell
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