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MW 249.4 Da, Purity >99%. Cell-permeable c-Myc-Max dimerization inhibitor. Downregulates c-Myc expression and upregulates CDK inhibitors, p21 and p27. Inhibits proliferation. Induces apoptosis and cell cycle arrest in G0/G1 phase. Shows antitumor effects in vivo..

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CAS number

403811-55-2

Purity

> 99%

Form

Solid

Molecular weight

249.4 Da

Molecular formula

C12H11NOS2

PubChem identifier

1271002

Nature

Synthetic

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MW 249.4 Da, Purity >99%. Cell-permeable c-Myc-Max dimerization inhibitor. Downregulates c-Myc expression and upregulates CDK inhibitors, p21 and p27. Inhibits proliferation. Induces apoptosis and cell cycle arrest in G0/G1 phase. Shows antitumor effects in vivo..

Key facts

Purity

> 99%

PubChem identifier

1271002

Biochemical name

5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone

Biological description

Cell-permeable c-Myc-Max dimerization inhibitor. Downregulates c-Myc expression and upregulates CDK inhibitors, p21 and p27. Inhibits proliferation. Induces apoptosis and cell cycle arrest in G0/G1 phase. Shows antitumor effects in vivo.

Canonical SMILES

CCC1=CC=C(C=C1)C=C2C(=O)NC(=S)S2

Isomeric SMILES

CCC1=CC=C(C=C1)/C=C/2\C(=O)NC(=S)S2

InChI

InChI=1S/C12H11NOS2/c1-2-8-3-5-9(6-4-8)7-10-11(14)13-12(15)16-10/h3-7H,2H2,1H3,(H,13,14,15)/b10-7+

InChIKey

SVXDHPADAXBMFB-JXMROGBWSA-N

IUPAC name

(5E)-5-[(4-ethylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate long-term storage conditions

+4°C

Storage information

Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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