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AB275366

2', 7'-Dichlorofluorescein di-β-D-lactoside

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(1 Publication)

MW 1049.76 g/mol. Highly sensitive fluorescent substrate for measuring beta-lactosidase and glucosidase inside live cells. Retains fluorescence at low pH due to lower pKa than comparable fluorophores. Suitable for measuring activity in the acidic lysosome environment.
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Chemical Structure - 2', 7'-Dichlorofluorescein di-β-D-lactoside (AB275366)
  • Chemical Structure

Lab

Chemical Structure - 2', 7'-Dichlorofluorescein di-β-D-lactoside (AB275366)

Chemical structure of 2', 7'-Dichlorofluorescein di-beta-D-lactoside

Key facts

Form

Solid

form

Molecular weight

1049.76 g/mol

Nature

Synthetic

Solubility

Soluble in methanol.

Biological description

Highly sensitive fluorescent substrate for measuring beta-lactosidase and glucosidase inside live cells. Retains fluorescence at low pH due to lower pKa than comparable fluorophores. Suitable for measuring activity in the acidic lysosome environment.

Excitation/Emission

Ex: 495nm, Em: 529nm

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Complementary Products

Biochemicals

AB275319

DiD

Chemical Structure - DiD (AB275319)

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Biochemicals

AB273896

4-Methylumbelliferyl Beta-D-lactoside

Chemical Structure - 4-Methylumbelliferyl Beta-D-lactoside (AB273896)

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Biochemicals

AB275090

2-Chloro-4-nitrophenyl-Beta-D-lactoside

Chemical Structure - 2-Chloro-4-nitrophenyl-Beta-D-lactoside (AB275090)

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Biochemicals

AB120570

U 99194 maleate (PNU 99194), D3 antagonist

Chemical Structure - U 99194 maleate (PNU 99194), D3 antagonist (AB120570)

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

STAR protocols 2:100340 PubMed33659904

2021

Analysis of lysosomal hydrolase trafficking and activity in human iPSC-derived neuronal models.

Applications

Unspecified application

Species

Unspecified reactive species

Leah K Cuddy,Joseph R Mazzulli
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