MW 235.26 Da, Purity >97%. Competitive carboxypeptidase B2 (TAFIa) inhibitor. Shows complex fibrinolytic effects prolonging or shortening fibrinolysis.
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- The Journal of biological chemistry 278:8913-212003Stabilization versus inhibition of TAFIa by competitive inhibitors in vitro.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJohn B Walker,Bernadette Hughes,Ian James,Peter Haddock,Cornelis Kluft,Laszlo BajzarPubMed 12643276
- The Journal of biological chemistry 273:2127-351998Plasma and recombinant thrombin-activable fibrinolysis inhibitor (TAFI) and activated TAFI compared with respect to glycosylation, thrombin/thrombomodulin-dependent activation, thermal stability, and enzymatic properties.Applications:Unspecified applicationReactive species:Unspecified reactive speciesM B Boffa,W Wang,L Bajzar,M E NesheimPubMed 9442053
- Blood 88:2093-1001996The profibrinolytic effect of activated protein C in clots formed from plasma is TAFI-dependent.Applications:Unspecified applicationReactive species:Unspecified reactive speciesL Bajzar,M E Nesheim,P B TracyPubMed 8822928
Key facts
- CAS number
77482-44-1
- Purity
> 97%
- Form
Solid
- Molecular weight
235.26 Da
- Molecular formula
C7H13N3O4S
- PubChem identifier
3464
- Nature
Synthetic
Target data
Alternative names
CBPB1_HUMAN, CP B1, CPB, Carboxypeptidase B, Carboxypeptidase B1, Carboxypeptidase B1 (tissue), DKFZp779K1333, PASP, PCPB, Pancreas-specific protein, Pancreatic carboxypeptidase B, Pancreatic carboxypeptidase B1, Procarboxypeptidase B, Procarboxypeptidase B pancreatic, Protaminase, Tissue carboxypeptidase B
Recommended products
MW 235.26 Da, Purity >97%. Competitive carboxypeptidase B2 (TAFIa) inhibitor. Shows complex fibrinolytic effects prolonging or shortening fibrinolysis.
Alternative names
CBPB1_HUMAN, CP B1, CPB, Carboxypeptidase B, Carboxypeptidase B1, Carboxypeptidase B1 (tissue), DKFZp779K1333, PASP, PCPB, Pancreas-specific protein, Pancreatic carboxypeptidase B, Pancreatic carboxypeptidase B1, Procarboxypeptidase B, Procarboxypeptidase B pancreatic, Protaminase, Tissue carboxypeptidase B
Key facts
- CAS number
77482-44-1
- Purity
> 97%
- Form
Solid
- Molecular weight
235.26 Da
- Molecular formula
C7H13N3O4S
- PubChem identifier
3464
- Nature
Synthetic
- Solubility
Soluble in water to 50 mM.
- Biochemical name
Gemsa
- Biological description
Competitive carboxypeptidase B2 (TAFIa) inhibitor. Shows complex fibrinolytic effects prolonging or shortening fibrinolysis.
- Canonical SMILES
C(CSC(CC(=O)O)C(=O)O)N=C(N)N
- InChI
InChI=1S/C7H13N3O4S/c8-7(9)10-1-2-15-4(6(13)14)3-5(11)12/h4H,1-3H2,(H,11,12)(H,13,14)(H4,8,9,10)
- InChIKey
VKVCLXDFOQQABP-UHFFFAOYSA-N
- IUPAC name
2-[2-(diaminomethylideneamino)ethylsulfanyl]butanedioic acid
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
+4°C
- Storage information
The product can be stored for up to 12 months
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Chemical Structure - 2-Guanidinoethylmercaptosuccinic acid (GEMSA), carboxypeptidase B2 (TAFIa) inhibitor (ab145054)
2D chemical structure image of ab145054, 2-Guanidinoethylmercaptosuccinic acid (GEMSA), carboxypeptidase B2 (TAFIa) inhibitor
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