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AB146145

25-Hydroxycholesterol, cholesterol metabolite

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MW 402.65 g/mol. Cholesterol metabolite produced and secreted by macrophages in response to TLR activation. Regulates immune function and has a key role in the pathogenesis of atherosclerosis.
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Chemical Structure - 25-Hydroxycholesterol, cholesterol metabolite (AB146145)
  • Chemical Structure

Lab

Chemical Structure - 25-Hydroxycholesterol, cholesterol metabolite (AB146145)

2D chemical structure image of ab146145, 25-Hydroxycholesterol, cholesterol metabolite

Key facts

CAS number

2140-46-7

Form

Solid

form

Molecular weight

402.65 g/mol

Molecular formula

C<sub>2</sub><sub>7</sub>H<sub>4</sub><sub>6</sub>O<sub>2</sub>

Nature

Synthetic

Biological description

Cholesterol metabolite produced and secreted by macrophages in response to TLR activation. Regulates immune function and has a key role in the pathogenesis of atherosclerosis.

Isomeric smiles

CC(C)(O)CCC[C@@H](C)[C@H]4CC[C@@H]3[C@]4(C)CC[C@H]2[C@H]3CC=C1C[C@@H](O)CC[C@@]12C

InChi

InChI=1S/C27H46O2/c1-18(7-6-14-25(2,3)29)22-10-11-23-21-9-8-19-17-20(28)12-15-26(19,4)24(21)13-16-27(22,23)5/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1

InChiKey

INBGSXNNRGWLJU-ZHHJOTBYSA-N

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Complementary Products

Biochemicals

AB146146

20(S)-Hydroxycholesterol, Smoothened activator

Chemical Structure - 20(S)-Hydroxycholesterol, Smoothened activator (AB146146)

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Biochemicals

AB146144

7alpha-Hydroxycholesterol, Bile acid precursor

Chemical Structure - 7alpha-Hydroxycholesterol, Bile acid precursor (AB146144)

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Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

  • 5
  • 15
Primary Antibodies

AB125011

Anti-TSG101 antibody [EPR7130(B)]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry - Anti-TSG101 antibody [EPR7130(B)] (AB125011)

  • 4
  • 10

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