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AB142766

25-Hydroxyvitamin D3 (Calcifediol), metabolite of vitamin D3

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MW 400.6 Da, Purity >98%. Principal cholecalciferol (ab143594) metabolite. Downregulates TLR4 and JAK1/STAT3 signaling. Hydroxylates to calcitriol (ab141456) *in vivo*. Anti-inflammatory effects. Orally active.
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Chemical Structure - 25-Hydroxyvitamin D3 (Calcifediol), metabolite of vitamin D3 (AB142766)
  • Chemical Structure

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Chemical Structure - 25-Hydroxyvitamin D3 (Calcifediol), metabolite of vitamin D3 (AB142766)

2D chemical structure image of ab142766, 25-Hydroxyvitamin D3 (Calcifediol), metabolite of vitamin D3

Key facts

CAS number

19356-17-3

Purity

>98%

Form

Solid

form

Molecular weight

400.6 Da

Molecular formula

C<sub>2</sub><sub>7</sub>H<sub>4</sub><sub>4</sub>O<sub>2</sub>

PubChem

5283731

Nature

Synthetic

Solubility

Soluble in DMSO to 25 mM

Biochemical name

Calcifediol

Biological description

Principal cholecalciferol (ab143594) metabolite. Downregulates TLR4 and JAK1/STAT3 signaling. Hydroxylates to calcitriol (ab141456) *in vivo*. Anti-inflammatory effects. Orally active.

Canonical smiles

CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C

Isomeric smiles

C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C

InChi

InChI=1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1

InChiKey

JWUBBDSIWDLEOM-DTOXIADCSA-N

IUPAC Name

(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol

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Complementary Products

Proteins & Peptides

AB65866

Human IgE protein (Azide free)

SDS-PAGE - Human IgE protein (Azide free) (AB65866)

  • 4
  • 2
Primary Antibodies

AB219464

Anti-25-OH Vitamin D3 antibody [RM3]

Recombinant

Competitive ELISA - Anti-25-OH Vitamin D3 antibody [RM3] (AB219464)

  • 0
  • 0
Biochemicals

AB143594

Cholecalciferol (Vitamin D3), VDR activator

Chemical Structure - Cholecalciferol (Vitamin D3), VDR activator (AB143594)

  • 0
  • 0
Assay Kits

AB213966

25(OH) Vitamin D ELISA kit

ELISA - 25(OH) Vitamin D ELISA kit (AB213966)

  • 0
  • 0
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Product promise

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