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AB143756

3-BrB-PP1, Akt inhibitor

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(11 Publications)

MW 360.25 g/mol. Small molecule Akt inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
1 Images
Chemical Structure - 3-BrB-PP1, Akt inhibitor (AB143756)
  • Chemical Structure

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Chemical Structure - 3-BrB-PP1, Akt inhibitor (AB143756)

2D chemical structure image of ab143756, 3-BrB-PP1, Akt inhibitor

Key facts

CAS number

956025-99-3

Form

Solid

form

Molecular weight

360.25 g/mol

Molecular formula

C<sub>1</sub><sub>6</sub>H<sub>1</sub><sub>8</sub>BrN<sub>5</sub>

Nature

Synthetic

Biological description

Small molecule Akt inhibitor.

IUPAC Name

4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

Publications (11)

Recent publications for all applications. Explore the full list and refine your search

eLife 13: PubMed38289024

2024

Heat stress-induced activation of MAPK pathway attenuates Atf1-dependent epigenetic inheritance of heterochromatin in fission yeast.

Applications

Unspecified application

Species

Unspecified reactive species

Li Sun,Libo Liu,Chunlin Song,Yamei Wang,Quan-Wen Jin

microPublication biology 2023: PubMed37746062

2023

Polarity kinases that phosphorylate F-BAR protein Cdc15 have unique localization patterns during cytokinesis and contributions to preventing tip septation in .

Applications

Unspecified application

Species

Unspecified reactive species

Maya G Igarashi,Rahul Bhattacharjee,Alaina H Willet,Kathleen L Gould

eLife 12: PubMed37615341

2023

Rtf2 is important for replication fork barrier activity of via splicing of .

Applications

Unspecified application

Species

Unspecified reactive species

Alice M Budden,Murat Eravci,Adam T Watson,Eduard Campillo-Funollet,Antony W Oliver,Karel Naiman,Antony M Carr

Molecular cell 83:3140-3154.e7 PubMed37572670

2023

A peroxiredoxin-P38 MAPK scaffold increases MAPK activity by MAP3K-independent mechanisms.

Applications

Unspecified application

Species

Unspecified reactive species

Min Cao,Alison M Day,Martin Galler,Heather R Latimer,Dominic P Byrne,Thomas W Foy,Emilia Dwyer,Elise Bennett,Jeremy Palmer,Brian A Morgan,Patrick A Eyers,Elizabeth A Veal

eLife 12: PubMed36825780

2023

Myosin II regulatory light chain phosphorylation and formin availability modulate cytokinesis upon changes in carbohydrate metabolism.

Applications

Unspecified application

Species

Unspecified reactive species

Francisco Prieto-Ruiz,Elisa Gómez-Gil,Rebeca Martín-García,Armando Jesús Pérez-Díaz,Jero Vicente-Soler,Alejandro Franco,Teresa Soto,Pilar Pérez,Marisa Madrid,José Cansado

eLife 12: PubMed36749320

2023

Multiple polarity kinases inhibit phase separation of F-BAR protein Cdc15 and antagonize cytokinetic ring assembly in fission yeast.

Applications

Unspecified application

Species

Unspecified reactive species

Rahul Bhattacharjee,Aaron R Hall,MariaSanta C Mangione,Maya G Igarashi,Rachel H Roberts-Galbraith,Jun-Song Chen,Dimitrios Vavylonis,Kathleen L Gould

Wellcome open research 6:44 PubMed33796794

2021

Increased expression of Polδ does not alter the canonical replication program .

Applications

Unspecified application

Species

Unspecified reactive species

Róbert Zach,Antony M Carr

eLife 9: PubMed32915139

2020

Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels.

Applications

Unspecified application

Species

Unspecified reactive species

Elisa Gómez-Gil,Rebeca Martín-García,Jero Vicente-Soler,Alejandro Franco,Beatriz Vázquez-Marín,Francisco Prieto-Ruiz,Teresa Soto,Pilar Pérez,Marisa Madrid,Jose Cansado

Current biology : CB 29:1379-1386.e4 PubMed30955932

2019

Noisy Cell-Size-Correlated Expression of Cyclin B Drives Probabilistic Cell-Size Homeostasis in Fission Yeast.

Applications

Unspecified application

Species

Unspecified reactive species

James O Patterson,Paul Rees,Paul Nurse

Oncotarget 9:28625-28637 PubMed29983885

2018

RIOK1 kinase activity is required for cell survival irrespective of status.

Applications

Unspecified application

Species

Unspecified reactive species

Alexandra Hörmann,Barbara Hopfgartner,Thomas Köcher,Maja Corcokovic,Teresa Krammer,Christoph Reiser,Gerd Bader,Junwei Shi,Katharina Ehrenhöfer,Simon Wöhrle,Norbert Schweifer,Christopher R Vakoc,Norbert Kraut,Mark Pearson,Mark Petronczki,Ralph A Neumüller
View all publications

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