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MW 119.08 Da, Purity >97%. Selective, irreversible succinic dehydrogenase (complex II) inhibitor. Induces mitochondrial citric acid cycle dysfunction, oxidative stress and cell death. Activates the Keap1-Nrf2-ARE pathway. Inhibits the MAPK and NF-κB pathways. Shows neurotoxic effects in vivo. .
- CAS number
504-88-1
- Purity
> 97%
- Form
Solid
- Molecular weight
119.08 Da
- Molecular formula
C3H5NO4
- PubChem identifier
1678
- Nature
Synthetic
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MW 119.08 Da, Purity >97%. Selective, irreversible succinic dehydrogenase (complex II) inhibitor. Induces mitochondrial citric acid cycle dysfunction, oxidative stress and cell death. Activates the Keap1-Nrf2-ARE pathway. Inhibits the MAPK and NF-κB pathways. Shows neurotoxic effects in vivo. .
Key facts
- CAS number
504-88-1
- Purity
> 97%
- Form
Solid
- Molecular weight
119.08 Da
- Molecular formula
C3H5NO4
- PubChem identifier
1678
- Nature
Synthetic
- Solubility
Very soluble in water, ethanol, diethyl ether; soluble in warm chloroform; insoluble in ligroin.
- Biochemical name
3-Nitropropionic acid
- Biological description
Selective, irreversible succinic dehydrogenase (complex II) inhibitor. Induces mitochondrial citric acid cycle dysfunction, oxidative stress and cell death. Activates the Keap1-Nrf2-ARE pathway. Inhibits the MAPK and NF-κB pathways. Shows neurotoxic effects in vivo.
- Canonical SMILES
C(C[N+](=O)[O-])C(=O)O
- InChI
InChI=1S/C3H5NO4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)
- InChIKey
WBLZUCOIBUDNBV-UHFFFAOYSA-N
- IUPAC name
3-nitropropanoic acid
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
-20°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
Notes
This product is manufactured by BioVision, an Abcam company and was previously called 2093 3-Nitropropionic acid. 2093-250 is the same size as the 250 mg size of ab145589.
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