3,3'-Diindolylmethane (DIM), antitumor agent

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MW 246.31 Da, Purity >98%. Diindolylmethane (DIM) is a natural compound present in food plants of the Brassica genus, including broccoli, cabbage, Brussels sprouts, cauliflower and kale. Displays antitumor and proapoptotic properties in animal and in in vitro models of cancer. Also acts a selective and potent inhibitor of cancer stem cells, and HDAC activity in prostate cancer cells. Recently, it has been shown that DIM induces apoptosis in ovarian cancer cells by inhibiting JAK2/STAT3.

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1 25 dihydroxyvitamin D3 receptor, 25-dihydroxyvitamin D3 receptor, AHR_HUMAN, Ah receptor, Aromatic hydrocarbon receptor, Aryl hydrocarbon receptor, Aryl hydrocarbon receptor precursor, Class E basic helix-loop-helix protein 76, EX 33, G protein coupled receptor EX 33, G-protein coupled receptor 84, GPCR 4, GPCR EX33, GPR84_HUMAN, HGNC:348, Inflammation related G protein coupled receptor EX 33, Inflammation-related G-protein coupled receptor EX33, Lymphocytic choriomeningitis virus, Member 1, NR1I1, Nuclear receptor subfamily 1 group I member 1, PPP1R163, Protein phosphatase 1, regulatory subunit 163, VDR_HUMAN, Vitamin D (1,25- dihydroxyvitamin D3) receptor, Vitamin D hormone receptor, Vitamin D nuclear receptor variant 1, Vitamin D receptor, Vitamin D3 receptor, bHLHe76