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AB275048

4-Methylumbelliferyl 4-guanidinobenzoate hydrochloride hydrate

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(3 Publications)

MW 373.8 Da, Purity >95%. Highly sensitive spectrofluorometric titrant for chymotrypsin, trypsin, thrombin, and factor Xa. Produces 4-methylumbelliferone with Ex/Em - 365/445 nm.
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Chemical Structure - 4-Methylumbelliferyl 4-guanidinobenzoate hydrochloride hydrate (AB275048)
  • Chemical Structure

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Chemical Structure - 4-Methylumbelliferyl 4-guanidinobenzoate hydrochloride hydrate (AB275048)

Chemical structure of 4-Methylumbelliferyl 4-guanidinobenzoate hydrochloride hydrate, 34197-46-1

Key facts

CAS number

34197-46-1

Purity

>95%

Form

Solid

form

Molecular weight

373.8 Da

Molecular formula

C<sub>1</sub><sub>8</sub>H<sub>1</sub><sub>6</sub>ClN<sub>3</sub>O<sub>4</sub>

PubChem

147561

Nature

Synthetic

Solubility

Soluble in DMSO

Biochemical name

4-Methyl-2-oxo-2H-1-benzopyran-7-yl 4-guanidinobenzoate monohydrochloride

Biological description

Highly sensitive spectrofluorometric titrant for chymotrypsin, trypsin, thrombin, and factor Xa. Produces 4-methylumbelliferone with Ex/Em - 365/445 nm.

Canonical smiles

CC1=CC(=O)OC2=C1C=CC(=C2)OC(=O)C3=CC=C(C=C3)N=C(N)N.Cl

InChi

InChI=1S/C18H15N3O4.ClH/c1-10-8-16(22)25-15-9-13(6-7-14(10)15)24-17(23)11-2-4-12(5-3-11)21-18(19)20;/h2-9H,1H3,(H4,19,20,21);1H

InChiKey

DAFWZROYEOVJAL-UHFFFAOYSA-N

IUPAC Name

(4-methyl-2-oxochromen-7-yl) 4-(diaminomethylideneamino)benzoate;hydrochloride

Excitation/Emission

Ex: 360nm, Em: 449nm

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store in the dark|Store under desiccating conditions
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Product protocols

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Biochemistry 54:3960-8 PubMed26029848

2015

Preferential Acquisition and Activation of Plasminogen Glycoform II by PAM Positive Group A Streptococcal Isolates.

Applications

Unspecified application

Species

Unspecified reactive species

David M P De Oliveira,Ruby H P Law,Diane Ly,Simon M Cook,Adam J Quek,Jason D McArthur,James C Whisstock,Martina L Sanderson-Smith

Molecular microbiology 86:1052-62 PubMed23106864

2012

Streptokinase variants from Streptococcus pyogenes isolates display altered plasminogen activation characteristics - implications for pathogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Simon M Cook,Amanda Skora,Christine M Gillen,Mark J Walker,Jason D McArthur

The Biochemical journal 131:107-17 PubMed4737291

1973

Determination of the operational molarity of solutions of bovine alpha-chymotrypsin, trypsin, thrombin and factor Xa by spectrofluorimetric titration.

Applications

Unspecified application

Species

Unspecified reactive species

G W Jameson,D V Roberts,R W Adams,W S Kyle,D T Elmore
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