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AB145305

5-Aminofluorescein (Fluoresceinamine, isomer I), Fluorescence marker

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(1 Publication)

MW 347.3 Da, Purity >95%. Fluorescence marker. Selectively targets malignant glioma tissue in vivo when covalently linked to human serum albumin at a molar ratio of 1:1without bleaching nor penetrating into surrounding brain edema or necrotic tissue. Blood-brain barrier permeable.
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Chemical Structure - 5-Aminofluorescein (Fluoresceinamine, isomer I), Fluorescence marker (AB145305)
  • Chemical Structure

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Chemical Structure - 5-Aminofluorescein (Fluoresceinamine, isomer I), Fluorescence marker (AB145305)

2D chemical structure image of ab145305, 5-Aminofluorescein (Fluoresceinamine, isomer I), Fluorescence marker

Key facts

CAS number

3326-34-9

Purity

>95%

Form

Solid

form

Molecular weight

347.3 Da

Molecular formula

C<sub>2</sub><sub>0</sub>H<sub>1</sub><sub>3</sub>NO<sub>5</sub>

PubChem

76845

Nature

Synthetic

Biochemical name

5-Aminofluorescein

Biological description

Fluorescence marker. Selectively targets malignant glioma tissue in vivo when covalently linked to human serum albumin at a molar ratio of 1:1without bleaching nor penetrating into surrounding brain edema or necrotic tissue. Blood-brain barrier permeable.

Canonical smiles

C1=CC2=C(C=C1N)C(=O)OC23C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O

InChi

InChI=1S/C20H13NO5/c21-10-1-4-14-13(7-10)19(24)26-20(14)15-5-2-11(22)8-17(15)25-18-9-12(23)3-6-16(18)20/h1-9,22-23H,21H2

InChiKey

GZAJOEGTZDUSKS-UHFFFAOYSA-N

IUPAC Name

6-amino-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one

Excitation/Emission

Ex: 490nm, Em: 520nm

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

eLife 13: PubMed39641975

2024

Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration.

Applications

Unspecified application

Species

Unspecified reactive species

Debabrata Dey,Shir Marciano,Anna Poryval,Ondřej Groborz,Lucie Wohlrabova,Tomás Slanina,Gideon Schreiber
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