MW 268.22 Da, Purity >99%. Uridine (ab143255) analog. Click chemistry RNA transcription label. Incorporates into RNA during active RNA synthesis. Does not incorporate into DNA. Reacts with azide-containing detection reagents.
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- Nucleic acids research 51:9019-90382023Deciphering a global source of non-genetic heterogeneity in cancer cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJianhan Zhang,Xu Han,Liang Ma,Shuhui Xu,Yihan LinPubMed 37587722
- eLife 9:2020Translation in amino-acid-poor environments is limited by tRNA charging.Applications:Unspecified applicationReactive species:Unspecified reactive speciesNatalya N Pavlova et. al.PubMed 33289483
- Molecular cell 78:127-140.e72020Cohesin Removal Reprograms Gene Expression upon Mitotic Entry.Applications:Unspecified applicationReactive species:Unspecified reactive speciesCarlos Perea-Resa et. al.PubMed 32035037
- The Journal of cell biology 216:2391-24072017Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesArchana Bairavasundaram Prusty et. al.PubMed 28637748
- The Journal of toxicological sciences 39:293-92014An RNA synthesis inhibition assay for detecting toxic substances using click chemistry.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYukiko Kametani,Shigenori Iwai,Isao KuraokaPubMed 24646711
- Journal of visualized experiments : JoVE :2013Using click chemistry to measure the effect of viral infection on host-cell RNA synthesis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesBirte Kalveram et. al.PubMed 23963093
- Analytical biochemistry 434:128-3520125-Ethynylcytidine as a new agent for detecting RNA synthesis in live cells by "click" chemistry.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDezhong Qu,Li Zhou,Wei Wang,Zhe Wang,Guoxin Wang,Weilin Chi,Biliang ZhangPubMed 23219562
Key facts
- CAS number
69075-42-9
- Purity
> 99%
- Molecular weight
268.22 Da
- Molecular formula
C11H12N2O6
- PubChem identifier
14885960
- Nature
Synthetic
Target data
Recommended products
MW 268.22 Da, Purity >99%. Uridine (ab143255) analog. Click chemistry RNA transcription label. Incorporates into RNA during active RNA synthesis. Does not incorporate into DNA. Reacts with azide-containing detection reagents.
Key facts
- CAS number
69075-42-9
- Purity
> 99%
- Molecular weight
268.22 Da
- Molecular formula
C11H12N2O6
- PubChem identifier
14885960
- Nature
Synthetic
- Solubility
Soluble in water to 100 mM.
- Biochemical name
5-Ethynyluridine
- Biological description
Uridine (ab143255) analog. Click chemistry RNA transcription label. Incorporates into RNA during active RNA synthesis. Does not incorporate into DNA. Reacts with azide-containing detection reagents.
- Canonical SMILES
C#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
- Isomeric SMILES
C#CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
- InChI
InChI=1S/C11H12N2O6/c1-2-5-3-13(11(18)12-9(5)17)10-8(16)7(15)6(4-14)19-10/h1,3,6-8,10,14-16H,4H2,(H,12,17,18)/t6-,7-,8-,10-/m1/s1
- InChIKey
QCWBIPKYTBFWHH-FDDDBJFASA-N
- IUPAC name
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-ethynylpyrimidine-2,4-dione
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
-20°C
- Storage information
Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
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1 product image
Chemical Structure - 5-Ethynyluridine (5-EU), Uridine analog (ab146642)
2D chemical structure image of ab146642, 5-Ethynyluridine (5-EU), Uridine analog
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