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AB141672

5-Hydroxydecanoate sodium salt, K+ channel blocker

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(1 Publication)

MW 210.25 Da. Mitochondrial KATP channel inhibitor. Inhibits the proliferation of hypoxic human pulmonary artery smooth muscle cells (HPASMC) by blocking mitochondrial KATP channels. Active *in vivo.*.
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Chemical Structure - 5-Hydroxydecanoate sodium salt, K+ channel blocker (AB141672)
  • Chemical Structure

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Chemical Structure - 5-Hydroxydecanoate sodium salt, K+ channel blocker (AB141672)

2D chemical structure image of ab141672, 5-Hydroxydecanoate sodium salt, K+ channel blocker

Key facts

CAS number

71186-53-3

Form

Solid

form

Molecular weight

210.25 Da

Molecular formula

C<sub>1</sub><sub>0</sub>H<sub>1</sub><sub>9</sub>NaO<sub>3</sub>

PubChem

23676659

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biochemical name

Sodium 5-hydroxydecanoate

Biological description

Mitochondrial KATP channel inhibitor. Inhibits the proliferation of hypoxic human pulmonary artery smooth muscle cells (HPASMC) by blocking mitochondrial KATP channels. Active *in vivo.*

Canonical smiles

CCCCCC(CCCC(=O)[O-])O.[Na+]

InChi

InChI=1S/C10H20O3.Na/c1-2-3-4-6-9(11)7-5-8-10(12)13;/h9,11H,2-8H2,1H3,(H,12,13);/q;+1/p-1

InChiKey

YNAGNECWEKMWRM-UHFFFAOYSA-M

IUPAC Name

sodium;5-hydroxydecanoate

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

Publications (1)

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Experimental and therapeutic medicine 22:836 PubMed34149882

2021

Hydrogen gas post-conditioning attenuates early neuronal pyroptosis in a rat model of subarachnoid hemorrhage through the mitoK signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Chuan-Suo Zhang,Qian Han,Zhao-Wei Song,Hong-Yan Jia,Tian-Peng Shao,Yan-Peng Chen
View all publications

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