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AB145438

5-TAMRA (5-Carboxytetramethylrhodamine), Fluorescent dye for DNA, peptides and proteins

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(1 Publication)

MW 430.45 g/mol, Purity >97%. Fluorescent dye for DNA, peptides and proteins. Amine-reactive. Used for oligonucleotide labeling and automated DNA sequencing applications. TAMRA is often used as FRET acceptor for FAM fluorophore. Free 5(6)-TAMRA (ab145282) and 6-TAMRA (ab145338) isomer. 5-TAMRA N-succinimidyl ester (ab145433) precursor.
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Chemical Structure - 5-TAMRA (5-Carboxytetramethylrhodamine), Fluorescent dye for DNA, peptides and proteins (AB145438)
  • Chemical Structure

Lab

Chemical Structure - 5-TAMRA (5-Carboxytetramethylrhodamine), Fluorescent dye for DNA, peptides and proteins (AB145438)

2D chemical structure image of ab145438, 5-TAMRA (5-Carboxytetramethylrhodamine), Fluorescent dye for DNA, peptides and proteins

Key facts

CAS number

91809-66-4

Purity

>97%

Form

Solid

form

Molecular weight

430.45 g/mol

Molecular formula

C<sub>2</sub><sub>5</sub>H<sub>2</sub><sub>2</sub>N<sub>2</sub>O<sub>5</sub>

Nature

Synthetic

Solubility

Soluble in DMSO

Biological description

Fluorescent dye for DNA, peptides and proteins. Amine-reactive. Used for oligonucleotide labeling and automated DNA sequencing applications. TAMRA is often used as FRET acceptor for FAM fluorophore. Free 5(6)-TAMRA (ab145282) and 6-TAMRA (ab145338) isomer. 5-TAMRA N-succinimidyl ester (ab145433) precursor.

Canonical smiles

CN(C)C4CC5OC1CC(CCC1C3(OC(=O)C2CC(CCC23)C(=O)O)C5CC4)N(C)C

InChi

InChI=1S/C25H22N2O5/c1-26(2)15-6-9-19-21(12-15)31-22-13-16(27(3)4)7-10-20(22)25(19)18-8-5-14(23(28)29)11-17(18)24(30)32-25/h5-13H,1-4H3,(H,28,29)

InChiKey

DCVXPZDNLDPUES-UHFFFAOYSA-N

IUPAC Name

5-Carboxytetramethylrhodamine

Excitation/Emission

Ex: 546nm, Em: 579nm

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cells 13: PubMed39768160

2025

Distinct UPR and Autophagic Functions Define Cell-Specific Responses to Proteotoxic Stress in Microglial and Neuronal Cell Lines.

Applications

Unspecified application

Species

Unspecified reactive species

Helena Domínguez-Martín,Elena Gavilán,Celia Parrado,Miguel A Burguillos,Paula Daza,Diego Ruano
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Complementary Products

Biochemicals

AB145433

5-TAMRA N-succinimidyl ester (5-Carboxy-tetramethylrhodamine N-succinimidyl ester)

Chemical Structure - 5-TAMRA N-succinimidyl ester (5-Carboxy-tetramethylrhodamine N-succinimidyl ester) (AB145433)

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Biochemicals

AB275361

5(6)-Carboxytetramethylrhodamine (TAMRA)

Chemical Structure - 5(6)-Carboxytetramethylrhodamine (TAMRA) (AB275361)

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Biochemicals

AB145334

6-TAMRA N-succinimidyl ester (6-TAMRA SE), Fluorophore for conjugation

Chemical Structure - 6-TAMRA N-succinimidyl ester (6-TAMRA SE), Fluorophore for conjugation (AB145334)

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Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

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