5(6)-Carboxyeosin

Key facts

CAS number

132201-84-4

Purity

>98%

Form

Solid

form

Molecular weight

1383.8 Da

Molecular formula

C₄₂H₁₆Br₈O₁₄

PubChem

133611923

Nature

Synthetic

Solubility

Soluble in DMSO

Biochemical name

4-(2,4,5,7-Tetrabromo-3-hydroxy-6-oxoxanthen-9-yl)benzene-1,3-dicarboxylic acid;2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxoxanthen-9-yl)terephthalic acid

Biological description

Brominated analog of carboxyfluorescein that is a photosensitizer and singlet oxygen generator (19 times greater than fluorescein). Specific PMCA (plasma membrane calcium pump) inhibitor.

Canonical smiles

C1=CC(=C(C=C1C(=O)O)C(=O)O)C2=C3C=C(C(=O)C(=C3OC4=C(C(=C(C=C24)Br)O)Br)Br)Br.C1=CC(=C(C=C1C(=O)O)C2=C3C=C(C(=O)C(=C3OC4=C(C(=C(C=C24)Br)O)Br)Br)Br)C(=O)O

InChi

InChI=1S/2C21H8Br4O7/c22-11-4-9-13(8-3-6(20(28)29)1-2-7(8)21(30)31)10-5-12(23)17(27)15(25)19(10)32-18(9)14(24)16(11)26;22-11-4-9-13(7-2-1-6(20(28)29)3-8(7)21(30)31)10-5-12(23)17(27)15(25)19(10)32-18(9)14(24)16(11)26/h2*1-5,26H,(H,28,29)(H,30,31)

InChiKey

XCIOXTCLDVENCD-UHFFFAOYSA-N

IUPAC Name

4-(2,4,5,7-tetrabromo-3-hydroxy-6-oxoxanthen-9-yl)benzene-1,3-dicarboxylic acid;2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxoxanthen-9-yl)terephthalic acid