5(6)-Carboxytetramethylrhodamine (TAMRA)

Key facts

CAS number

98181-63-6

Purity

>90%

Form

Solid

form

Molecular weight

860.9 Da

Molecular formula

C₅₀H₄₄N₄O₁₀

PubChem

56846372

Nature

Synthetic

Solubility

Soluble in DMSO.

Biochemical name

5(6)-Carboxytetramethylrhodamine

Biological description

Fluorescent dye that is used to label oligonucleotides at the 5'- or 3'-ends, or internally. It is also used for protein labeling where it can be added to the amino terminal or to lysine residues.

Canonical smiles

CN(C)C1=CC2=C(C=C1)C3(C4=C(C=C(C=C4)C(=O)O)C(=O)O3)C5=C(O2)C=C(C=C5)N(C)C.CN(C)C1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)N(C)C)C5=C(C=CC(=C5)C(=O)O)C(=O)O3

InChi

InChI=1S/2C25H22N2O5/c1-26(2)15-6-9-19-21(12-15)31-22-13-16(27(3)4)7-10-20(22)25(19)18-8-5-14(23(28)29)11-17(18)24(30)32-25;1-26(2)15-6-9-18-21(12-15)31-22-13-16(27(3)4)7-10-19(22)25(18)20-11-14(23(28)29)5-8-17(20)24(30)32-25/h2*5-13H,1-4H3,(H,28,29)

InChiKey

LBUFYZITRTUEFI-UHFFFAOYSA-N

IUPAC Name

3',6'-bis(dimethylamino)-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid;3',6'-bis(dimethylamino)-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid

Excitation/Emission

Ex: 565nm, Em: 580nm