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AB274312

6-Amino-D-luciferin

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(3 Publications)

MW 279.3 Da. Amino analog of the common D-luciferin substrate. Cell permeable reagent that measures firefly luciferase activity. Ideal for the design of proluminescent bioconjugates (peptidase substrates) of luciferin used in ultrasensitive luminescent assays.
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Chemical Structure - 6-Amino-D-luciferin (AB274312)
  • Chemical Structure

Lab

Chemical Structure - 6-Amino-D-luciferin (AB274312)

Chemical structure of 6-Amino-D-luciferin, 161055-47-6

Key facts

CAS number

118969-27-0

Form

Solid

form

Molecular weight

279.3 Da

Molecular formula

C<sub>1</sub><sub>1</sub>H<sub>9</sub>N<sub>3</sub>O<sub>2</sub>S<sub>2</sub>

PubChem

2762583

Nature

Synthetic

Solubility

Soluble in DMSO

Biochemical name

2-(6-Amino-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid

Biological description

Amino analog of the common D-luciferin substrate. Cell permeable reagent that measures firefly luciferase activity. Ideal for the design of proluminescent bioconjugates (peptidase substrates) of luciferin used in ultrasensitive luminescent assays.

Canonical smiles

C1C(N=C(S1)C2=NC3=C(S2)C=C(C=C3)N)C(=O)O

InChi

InChI=1S/C11H9N3O2S2/c12-5-1-2-6-8(3-5)18-10(13-6)9-14-7(4-17-9)11(15)16/h1-3,7H,4,12H2,(H,15,16)

InChiKey

HKSJKXOOBAVPKR-UHFFFAOYSA-N

IUPAC Name

2-(6-amino-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions
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Product protocols

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Proceedings of the National Academy of Sciences of the United States of America 111:4443-8 PubMed24616520

2014

Latent luciferase activity in the fruit fly revealed by a synthetic luciferin.

Applications

Unspecified application

Species

Unspecified reactive species

David M Mofford,Gadarla Randheer Reddy,Stephen C Miller

Chemistry & biology 18:1649-57 PubMed22195567

2011

Identification of mutant firefly luciferases that efficiently utilize aminoluciferins.

Applications

Unspecified application

Species

Unspecified reactive species

Katryn R Harwood,David M Mofford,Gadarla R Reddy,Stephen C Miller

Biochemistry 45:11103-12 PubMed16964971

2006

Luciferin derivatives for enhanced in vitro and in vivo bioluminescence assays.

Applications

Unspecified application

Species

Unspecified reactive species

Rajesh Shinde,Julie Perkins,Christopher H Contag
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