6-p-Toluidino-2-naphthalenesulfonic acid

Key facts

CAS number

7724-15-4

Purity

>98%

Form

Solid

form

Molecular weight

313.4 Da

Molecular formula

C₁₇H₁₅NO₃S

PubChem

82178

Nature

Synthetic

Solubility

Soluble in DMSO

Slightly soluble in water

Biochemical name

2-Naphthalenesulfonic acid, 6-[(4-methylphenyl)amino]-

Biological description

Environmentally sensitive fluorescent probe for the conformational state of proteins. Non-fluorescent in water, becoming fluorescent when bound to membranes (q.y. ~0.27) or proteins (q.y. ~0.72). The fluorescence is also enhanced by cyclodextrins, permitting a sensitive method for separating and analyzing cyclodextrins with capillary electrophoresis.

Canonical smiles

CC1=CC=C(C=C1)NC2=CC3=C(C=C2)C=C(C=C3)S(=O)(=O)O

InChi

InChI=1S/C17H15NO3S/c1-12-2-6-15(7-3-12)18-16-8-4-14-11-17(22(19,20)21)9-5-13(14)10-16/h2-11,18H,1H3,(H,19,20,21)

InChiKey

VTRBOZNMGVDGHY-UHFFFAOYSA-N

IUPAC Name

6-(4-methylanilino)naphthalene-2-sulfonic acid