6-p-Toluidino-2-naphthalenesulfonic acid, potassium salt (TNS-K+)

Key facts

CAS number

32752-10-6

Purity

>98%

Form

Solid

form

Molecular weight

351.5 Da

Molecular formula

C₁₇H₁₄KNO₃S

PubChem

23666335

Nature

Synthetic

Solubility

Soluble in DMSO

Soluble in water

Biochemical name

Potassium 6-(p-toluidino)naphthalene-2-sulphonate

Biological description

Fluorescent probe for measuring protein conformational changes and quantitative measurement of protein hydrophobicity processes that modify the exposure of the probe to water. Essentially nonfluorescent in water. Fluorescent when bound to membranes (q.y. ~0.27) or hydrophobic domains of proteins (q.y. ~0.72). Fluorescence enhanced by cyclodextrins. Can be used to provide a sensitive method for separating and analyzing cyclodextrins by capillary electrophoresis.

Canonical smiles

CC1=CC=C(C=C1)NC2=CC3=C(C=C2)C=C(C=C3)S(=O)(=O)[O-].[K+]

InChi

InChI=1S/C17H15NO3S.K/c1-12-2-6-15(7-3-12)18-16-8-4-14-11-17(22(19,20)21)9-5-13(14)10-16;/h2-11,18H,1H3,(H,19,20,21);/q;+1/p-1

InChiKey

GVDCHDBOXJUSDZ-UHFFFAOYSA-M

IUPAC Name

potassium;6-(4-methylanilino)naphthalene-2-sulfonate

Excitation/Emission

Ex: 318nm, Em: 443nm