AB146746
6-Thio-GTP (aqueous solution) (Thiogtp), Vac-1-Rac signaling inhibitor
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(1 Publication)
MW 539.24 g/mol, Purity >95%. Vac-1-Rac signaling inhibitor. Azathioprine (ab143064) metabolite. 6-mercaptopurine (ab142389) derivative. Inhibits TNF-α-induced downstream signaling via JNK. Reduces c-Jun, transcription factor-2 and NF-κB activation. Shows immunosuppressant effects.
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- Chemical Structure
Lab
Chemical Structure - 6-Thio-GTP (aqueous solution) (Thiogtp), Vac-1-Rac signaling inhibitor (AB146746)
2D chemical structure image of ab146746, 6-Thio-GTP (aqueous solution) (Thiogtp), Vac-1-Rac signaling inhibitor
Properties and storage information
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions
Publications (1)
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International journal of molecular sciences 25: PubMed39519032
2024
Dennd2c Negatively Controls Multinucleation and Differentiation in Osteoclasts by Regulating Actin Polymerization and Protrusion Formation.
Applications
Unspecified application
Species
Unspecified reactive species
Yu Koyanagi,Eiko Sakai,Yu Yamaguchi,Fatima Farhana,Yohsuke Taira,Kuniaki Okamoto,Hiroshi Murata,Takayuki Tsukuba
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