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MW 152.11 g/mol, Purity >99%. Purine analogue with potential antineoplastic activity. Antimetabolite. Competes with guanine. Incorporated into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth. Has been used in the treatment of acute leukemia.

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Images

Chemical Structure - 8-Azaguanine, purine analogue with antineoplastic activity (AB145798), expandable thumbnail

Key facts

CAS number
134-58-7
Purity
> 99%
Form
Solid
Molecular weight
152.11 g/mol
Molecular formula
C4H4N6O
Nature
Synthetic

Target data

Recommended products

MW 152.11 g/mol, Purity >99%. Purine analogue with potential antineoplastic activity. Antimetabolite. Competes with guanine. Incorporated into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth. Has been used in the treatment of acute leukemia.

Key facts

Purity
> 99%
Solubility

Soluble in DMSO to 25 mM (lot-dependent).

Biological description

Purine analogue with potential antineoplastic activity. Antimetabolite. Competes with guanine. Incorporated into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth. Has been used in the treatment of acute leukemia.

IUPAC name
5-Amino-3,6-dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - 8-Azaguanine, purine analogue with antineoplastic activity (ab145798), expandable thumbnail

    Chemical Structure - 8-Azaguanine, purine analogue with antineoplastic activity (ab145798)

    2D chemical structure image of ab145798, 8-Azaguanine, purine analogue with antineoplastic activity

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Product protocols

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