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AB145798

8-Azaguanine, purine analogue with antineoplastic activity

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MW 152.11 g/mol, Purity >99%. Purine analogue with potential antineoplastic activity. Antimetabolite. Competes with guanine. Incorporated into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth. Has been used in the treatment of acute leukemia.
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Chemical Structure - 8-Azaguanine, purine analogue with antineoplastic activity (AB145798)
  • Chemical Structure

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Chemical Structure - 8-Azaguanine, purine analogue with antineoplastic activity (AB145798)

2D chemical structure image of ab145798, 8-Azaguanine, purine analogue with antineoplastic activity

Key facts

CAS number

134-58-7

Purity

>99%

Form

Solid

form

Molecular weight

152.11 g/mol

Molecular formula

C<sub>4</sub>H<sub>4</sub>N<sub>6</sub>O

Nature

Synthetic

Solubility

Soluble in DMSO to 25 mM (lot-dependent)

Biological description

Purine analogue with potential antineoplastic activity. Antimetabolite. Competes with guanine. Incorporated into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth. Has been used in the treatment of acute leukemia.

IUPAC Name

5-Amino-3,6-dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

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