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MW 446.08 Da, Purity >95%. Cell permeable cGMP analog. PKG activator. Increases Ca2+ levels and active in vivo.

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Images

Chemical Structure - 8-Br-cGMP (8-Bromo-cGMP), PKG activator (AB141449), expandable thumbnail

Publications

Key facts

CAS number
51116-01-9
Purity
> 95%
Form
Solid
Molecular weight
446.08 Da
Molecular formula
C10H10BrN5NaO7P
PubChem identifier
44134592
Nature
Synthetic

Target data

Recommended products

MW 446.08 Da, Purity >95%. Cell permeable cGMP analog. PKG activator. Increases Ca2+ levels and active in vivo.

Key facts

Purity
> 95%
PubChem identifier
44134592
Solubility

Soluble in water to 50 mM.

Biochemical name
CID 44134592
Biological description

Cell permeable cGMP analog. PKG activator. Increases Ca2+ levels and active in vivo.

Canonical SMILES
C1C2C(C(C(O2)N3C4=C(C(=O)N=C(N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+]
Isomeric SMILES
C1C2C(C(C(O2)N3C4=C(C(=O)N=C(N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+]
InChI
InChI=1S/C10H11BrN5O7P.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5;/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18);/q;+1/p-1
InChIKey
ZJRFCXHKYQVNFK-UHFFFAOYSA-M
IUPAC name
sodium;2-amino-8-bromo-9-(7-hydroxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-3H-purin-6-one

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

Notes

This product is manufactured by BioVision, an Abcam company and was previously called 1838 8-Br-cGMP. 1838-25 is the same size as the 25 mg size of ab141449.

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1 product image

  • Chemical Structure - 8-Br-cGMP (8-Bromo-cGMP), PKG activator (ab141449), expandable thumbnail

    Chemical Structure - 8-Br-cGMP (8-Bromo-cGMP), PKG activator (ab141449)

    2D chemical structure image of ab141449, 8-Br-cGMP (8-Bromo-cGMP), PKG activator

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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