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MW 382.33 g/mol, Purity >98%.
Highly selective dopamine D4 receptor agonist at rat D4 and human D4.4 receptors (Ki values are 12.1 and 7.9 nM, respectively). Potent, full agonist at rat dopamine D4 receptors (EC50 = 28.4 nM). Superior selectivity profile to PD168077 (ab120568) and CP226269. No affinity for other dopamine receptors (Ki > 1 μM). Able to rapidly cross the blood-brain barrier following systemic administration.
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- CAS number
630116-49-3
- Purity
> 98%
- Form
Solid
- Molecular weight
382.33 g/mol
- Nature
Synthetic
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MW 382.33 g/mol, Purity >98%.
Highly selective dopamine D4 receptor agonist at rat D4 and human D4.4 receptors (Ki values are 12.1 and 7.9 nM, respectively). Potent, full agonist at rat dopamine D4 receptors (EC50 = 28.4 nM). Superior selectivity profile to PD168077 (ab120568) and CP226269. No affinity for other dopamine receptors (Ki > 1 μM). Able to rapidly cross the blood-brain barrier following systemic administration.
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Key facts
- CAS number
630116-49-3
- Purity
> 98%
- Form
Solid
- Molecular weight
382.33 g/mol
- Nature
Synthetic
- Biological description
Highly selective dopamine D4 receptor agonist at rat D4 and human D4.4 receptors (Ki values are 12.1 and 7.9 nM, respectively). Potent, full agonist at rat dopamine D4 receptors (EC50 = 28.4 nM). Superior selectivity profile to PD168077 (ab120568) and CP226269. No affinity for other dopamine receptors (Ki > 1 μM). Able to rapidly cross the blood-brain barrier following systemic administration.
- IUPAC name
N-(3-Methylphenyl)-2-[4-(2-pyridinyl)-1-piperidinyl]acetamide dihydrochloride
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
+4°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
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