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AB142809

A 943931 dihydrochloride, H4 receptor antagonist

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MW 368.3 Da, Purity >99%. Potent and selective H4 receptor antagonist (pKi = 7-8). Shows anti-inflammatory and analgesic effects *in vivo.* Orally active.
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Chemical Structure - A 943931 dihydrochloride, H4 receptor antagonist (AB142809)
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Chemical Structure - A 943931 dihydrochloride, H4 receptor antagonist (AB142809)

2D chemical structure image of ab142809, A 943931 dihydrochloride, H4 receptor antagonist

Key facts

CAS number

1227675-50-4

Purity

>99%

Form

Solid

form

Formulation

Constituents: 100% A 943931 dihydrochloride

Molecular weight

368.3 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>2</sub><sub>3</sub>Cl<sub>2</sub>N<sub>5</sub>

PubChem

56972240

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biochemical name

A 943931 dihydrochloride

Biological description

Potent and selective H4 receptor antagonist (pKi = 7-8). Shows anti-inflammatory and analgesic effects *in vivo.* Orally active.

Canonical smiles

C1CC2=CC=CC=C2C3=C(C1)C(=NC(=N3)N)N4CCC(C4)N.Cl.Cl

Isomeric smiles

C1CC2=CC=CC=C2C3=C(C1)C(=NC(=N3)N)N4CC[C@H](C4)N.Cl.Cl

InChi

InChI=1S/C17H21N5.2ClH/c18-12-8-9-22(10-12)16-14-7-3-5-11-4-1-2-6-13(11)15(14)20-17(19)21-16;;/h1-2,4,6,12H,3,5,7-10,18H2,(H2,19,20,21);2*1H/t12-;;/m1../s1

InChiKey

ISYUFRNZHUOGLA-CURYUGHLSA-N

IUPAC Name

6-[(3R)-3-aminopyrrolidin-1-yl]-3,5-diazatricyclo[9.4.0.02,7]pentadeca-1(15),2(7),3,5,11,13-hexaen-4-amine;dihydrochloride

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Complementary Products

Biochemicals

AB142807

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Biochemicals

AB142806

ION Potassium Green-2 AM, K+ indicator

Chemical Structure - ION Potassium Green-2 AM, K+ indicator (AB142806)

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Biochemicals

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Fluo-8 AM, green fluorescent calcium binding dye

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Biochemicals

AB241082

Fluo-4 AM, Fluorescent labeling reagent

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Product protocols

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Product promise

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