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AB142809

A 943931 dihydrochloride, H4 receptor antagonist

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MW 368.3 Da, Purity >99%. Potent and selective H4 receptor antagonist (pKi = 7-8). Shows anti-inflammatory and analgesic effects *in vivo.* Orally active.
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Chemical Structure - A 943931 dihydrochloride, H4 receptor antagonist (AB142809)
  • Chemical Structure

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Chemical Structure - A 943931 dihydrochloride, H4 receptor antagonist (AB142809)

2D chemical structure image of ab142809, A 943931 dihydrochloride, H4 receptor antagonist

Key facts

CAS number

1227675-50-4

Purity

>99%

Form

Solid

form

Molecular weight

368.3 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>2</sub><sub>3</sub>Cl<sub>2</sub>N<sub>5</sub>

PubChem

56972240

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biochemical name

A 943931 dihydrochloride

Biological description

Potent and selective H4 receptor antagonist (pKi = 7-8). Shows anti-inflammatory and analgesic effects *in vivo.* Orally active.

Canonical smiles

C1CC2=CC=CC=C2C3=C(C1)C(=NC(=N3)N)N4CCC(C4)N.Cl.Cl

Isomeric smiles

C1CC2=CC=CC=C2C3=C(C1)C(=NC(=N3)N)N4CC[C@H](C4)N.Cl.Cl

InChi

InChI=1S/C17H21N5.2ClH/c18-12-8-9-22(10-12)16-14-7-3-5-11-4-1-2-6-13(11)15(14)20-17(19)21-16;;/h1-2,4,6,12H,3,5,7-10,18H2,(H2,19,20,21);2*1H/t12-;;/m1../s1

InChiKey

ISYUFRNZHUOGLA-CURYUGHLSA-N

IUPAC Name

6-[(3R)-3-aminopyrrolidin-1-yl]-3,5-diazatricyclo[9.4.0.02,7]pentadeca-1(15),2(7),3,5,11,13-hexaen-4-amine;dihydrochloride

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months
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Product protocols

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