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AB141891

Acarbose, alpha-glucosidase inhibitor

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MW 645.6 Da, Purity >99%. Potent α-glucosidase inhibitor (IC50 = 11 nM). Orally active. Antidiabetic.

View Alternative Names

4-alpha-glucosidase, 70 kDa lysosomal alpha-glucosidase, Acid Maltase, Acid alpha glucosidase, Aglucosidase Alfa, Alpha-glucosidase, Glucan 1, Glucoamylase, Glucosidase alpha, Glucosidase alpha acid, Glucosidase alpha acid (Pompe disease glycogen storage disease type II), Isomaltase, LYAG_HUMAN, Lysosomal Alpha-Glucosidase, MGAML, MGA_HUMAN, MGC131621, MGC131622, Maltase-glucoamylase, intestinal, Oligosaccharide alpha 1, 6 glucosidase, SUIS_HUMAN, Sucrase-isomaltase, intestinal, sucrase isomaltase, sucrase isomaltase alpha glucosidase

1 Images
Chemical Structure - Acarbose, alpha-glucosidase inhibitor (AB141891)
  • Chemical Structure

Lab

Chemical Structure - Acarbose, alpha-glucosidase inhibitor (AB141891)

2D chemical structure image of ab141891, Acarbose, alpha-glucosidase inhibitor

Key facts

CAS number

56180-94-0

Purity

>99%

Form

Solid

form

Molecular weight

645.6 Da

Molecular formula

C<sub>2</sub><sub>5</sub>H<sub>4</sub><sub>3</sub>NO<sub>1</sub><sub>8</sub>

PubChem

41774

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Soluble in DMSO to 100 mM

Biochemical name

Precose

Biological description

Potent α-glucosidase inhibitor (IC50 = 11 nM). Orally active. Antidiabetic.

Canonical smiles

CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)NC4C=C(C(C(C4O)O)O)CO

Isomeric smiles

C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](OC([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO

InChi

InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23?,24-,25-/m1/s1

InChiKey

XUFXOAAUWZOOIT-UGEKTDRHSA-N

IUPAC Name

(3R,4R,5S,6R)-5-[(2R,3R,4R,5S,6R)-5-[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triol

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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