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AB142090

ACC2 Inhibitor, ACC2 (Acetyl-CoA Carboxylase) inhibitor

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(1 Publication)

MW 403.52 g/mol, Purity >98%. Potent, selective ACC2 (Acetyl-CoA Carboxylase) inhibitor (IC50 values are 28 and 210 nM for hACC2 and hACC1 respectively). Active in vivo and in vitro.
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Chemical Structure - ACC2 Inhibitor, ACC2 (Acetyl-CoA Carboxylase) inhibitor (AB142090)
  • Chemical Structure

Lab

Chemical Structure - ACC2 Inhibitor, ACC2 (Acetyl-CoA Carboxylase) inhibitor (AB142090)

2D chemical structure image of ab142090, ACC2 Inhibitor, ACC2 (Acetyl-CoA Carboxylase) inhibitor

Key facts

Purity

>98%

Form

Solid

form

Molecular weight

403.52 g/mol

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>2</sub><sub>1</sub>N<sub>3</sub>O<sub>3</sub>S<sub>2</sub>

Nature

Synthetic

Solubility

Soluble in DMSO

Biological description

Potent, selective ACC2 (Acetyl-CoA Carboxylase) inhibitor (IC50 values are 28 and 210 nM for hACC2 and hACC1 respectively). Active in vivo and in vitro.

Canonical smiles

CC(=O)NC(C)C1CNC(S1)C3CNC(OC2CCC(OC(C)C)CC2)S3

InChi

InChI=1S/C19H21N3O3S2c1-11(2)24-14-5-7-15(8-6-14)25-19-21-10-17(27-19)18-20-9-16(26-18)12(3)22-13(4)23/h5-12H,1-4H3,(H,22,23)

InChiKey

CVAJIWQTUPPAIF-UHFFFAOYSA-N

IUPAC Name

N-(1-(2'-(4-Isopropoxyphenoxy)-2,5'-bithiazol-5-yl)ethyl)acetamide

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 1717 ACC2 Inhibitor. 1717-1 is the same size as the 1 mg size of ab142090.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of clinical investigation 131: PubMed34255743

2021

WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis.

Applications

Unspecified application

Species

Unspecified reactive species

Julius Brandenburg,Sebastian Marwitz,Simone C Tazoll,Franziska Waldow,Barbara Kalsdorf,Tim Vierbuchen,Thomas Scholzen,Annette Gross,Svenja Goldenbaum,Alexandra Hölscher,Martina Hein,Lara Linnemann,Maja Reimann,Andreas Kispert,Michael Leitges,Jan Rupp,Christoph Lange,Stefan Niemann,Jochen Behrends,Torsten Goldmann,Holger Heine,Ulrich E Schaible,Christoph Hölscher,Dominik Schwudke,Norbert Reiling
View all publications
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Product promise

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