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AB142475

Aconitine, Voltage-gated Na+ channel activator

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MW 645.7 Da, Purity >88%. Voltage-gated Na+ channel activator. Binds to neurotoxin binding site 2 of the Na+ channel α-subunit. Shows arrhythmogenic effects in vivo. Orally active.
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Chemical Structure - Aconitine, Voltage-gated Na+ channel activator (AB142475)
  • Chemical Structure

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Chemical Structure - Aconitine, Voltage-gated Na+ channel activator (AB142475)

2D chemical structure image of ab142475, Aconitine, Voltage-gated Na+ channel activator

Key facts

CAS number

302-27-2

Purity

>88%

Molecular weight

645.7 Da

Molecular formula

C<sub>3</sub><sub>4</sub>H<sub>4</sub><sub>7</sub>NO<sub>1</sub><sub>1</sub>

PubChem

2012

Nature

Synthetic

Solubility

Soluble in ethanol to 50 mM

Biochemical name

Aconitinum

Biological description

Voltage-gated Na+ channel activator. Binds to neurotoxin binding site 2 of the Na+ channel α-subunit. Shows arrhythmogenic effects in vivo. Orally active.

Canonical smiles

CCN1CC2(C(CC(C34C2C(C(C31)C5(C6C4CC(C6OC(=O)C7=CC=CC=C7)(C(C5O)OC)O)OC(=O)C)OC)OC)O)COC

InChi

InChI=1S/C34H47NO11/c1-7-35-15-31(16-41-3)20(37)13-21(42-4)33-19-14-32(40)28(45-30(39)18-11-9-8-10-12-18)22(19)34(46-17(2)36,27(38)29(32)44-6)23(26(33)35)24(43-5)25(31)33/h8-12,19-29,37-38,40H,7,13-16H2,1-6H3

InChiKey

XFSBVAOIAHNAPC-UHFFFAOYSA-N

IUPAC Name

[8-acetyloxy-11-ethyl-5,7,14-trihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] benzoate

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months
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Product protocols

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