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MW 259.27 Da, Purity >99%. Selective platelet-derived growth factor receptor (PDGFR) kinase inhibitor (IC50 = 20 μM). Weak epidermal growth factor receptor (EGFR) inhibitor (IC50 = 820 μM). Blocks proliferative effect of PDGF.

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CAS number

134036-53-6

Purity

> 99%

Molecular weight

259.27 Da

Molecular formula

C15H9N5

PubChem identifier

5328748

Nature

Synthetic

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United States

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MW 259.27 Da, Purity >99%. Selective platelet-derived growth factor receptor (PDGFR) kinase inhibitor (IC50 = 20 μM). Weak epidermal growth factor receptor (EGFR) inhibitor (IC50 = 820 μM). Blocks proliferative effect of PDGF.

Key facts

Purity

> 99%

PubChem identifier

5328748

Biochemical name

(3Z)-2-amino-4-(1H-indol-5-yl)buta-1,3-diene-1,1,3-tricarbonitrile

Biological description

Selective platelet-derived growth factor receptor (PDGFR) kinase inhibitor (IC50 = 20 μM). Weak epidermal growth factor receptor (EGFR) inhibitor (IC50 = 820 μM). Blocks proliferative effect of PDGF.

Canonical SMILES

C1=CC2=C(C=CN2)C=C1C=C(C#N)C(=C(C#N)C#N)N

Isomeric SMILES

C1=CC2=C(C=CN2)C=C1/C=C(\C#N)/C(=C(C#N)C#N)N

InChI

InChI=1S/C15H9N5/c16-7-12(15(19)13(8-17)9-18)6-10-1-2-14-11(5-10)3-4-20-14/h1-6,20H,19H2/b12-6+

InChIKey

CMMDWEJTQUTCKG-WUXMJOGZSA-N

IUPAC name

(3Z)-2-amino-4-(1H-indol-5-yl)buta-1,3-diene-1,1,3-tricarbonitrile

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate long-term storage conditions

-20°C

Storage information

Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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