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AB141446

ALLM, calpain inhibitor

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(4 Publications)

MW 401.6 Da, Purity >95%. Achieve your results faster with highly validated, pure and trusted compounds.
1 Images
Chemical Structure - ALLM, calpain inhibitor (AB141446)
  • Chemical Structure

Lab

Chemical Structure - ALLM, calpain inhibitor (AB141446)

2D chemical structure image of ab141446, ALLM, calpain inhibitor

Key facts

Purity

>95%

Form

Solid

form

Molecular weight

401.6 Da

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>3</sub><sub>5</sub>N<sub>3</sub>O<sub>4</sub>S

PubChem

4331

Nature

Synthetic

Solubility

Soluble in DMSO to 50 mM

Soluble in ethanol to 50 mM

Biochemical name

Calpain inhibitor II

Canonical smiles

CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCSC)C=O)NC(=O)C

InChi

InChI=1S/C19H35N3O4S/c1-12(2)9-16(20-14(5)24)19(26)22-17(10-13(3)4)18(25)21-15(11-23)7-8-27-6/h11-13,15-17H,7-10H2,1-6H3,(H,20,24)(H,21,25)(H,22,26)

InChiKey

RJWLAIMXRBDUMH-UHFFFAOYSA-N

IUPAC Name

2-acetamido-4-methyl-N-[4-methyl-1-[(4-methylsulfanyl-1-oxobutan-2-yl)amino]-1-oxopentan-2-yl]pentanamide

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Complementary Products

Biochemicals

AB147047

MG-132 (Ethanol Solution), proteasome inhibitor

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Biochemicals

AB141003

MG-132, proteasome inhibitor

Immunocytochemistry/ Immunofluorescence - MG-132, proteasome inhibitor (AB141003)

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Biochemicals

AB142181

Cathepsin G Inhibitor, cathepsin G inhibitor

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Biochemicals

AB141464

PD 150606, Calpain inhibitor

Chemical Structure - PD 150606, Calpain inhibitor (AB141464)

  • 5
  • 1
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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 1835 Calpain Inhibitor II, ALLM. 1835-25 is the same size as the 25 mg size of ab141446.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

PloS one 20:e0316822 PubMed39841661

2025

Reduction of Cystatin B results in increased cathepsin B activity in disomic but not Trisomy 21 human cellular and mouse models.

Applications

Unspecified application

Species

Unspecified reactive species

Yixing Wu,Karen Cleverley,Frances K Wiseman

Acta neuropathologica communications 11:132 PubMed37580797

2023

Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B.

Applications

Unspecified application

Species

Unspecified reactive species

Yixing Wu,Paige Mumford,Suzanna Noy,Karen Cleverley,Alicja Mrzyglod,Dinghao Luo,Floris van Dalen,Martijn Verdoes,Elizabeth M C Fisher,Frances K Wiseman

PloS one 16:e0242236 PubMed34292972

2021

The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model.

Applications

Unspecified application

Species

Unspecified reactive species

Yixing Wu,Heather T Whittaker,Suzanna Noy,Karen Cleverley,Veronique Brault,Yann Herault,Elizabeth M C Fisher,Frances K Wiseman

Frontiers in cell and developmental biology 9:669086 PubMed34222239

2021

Junctional ER Organization Affects Mechanotransduction at Cadherin-Mediated Adhesions.

Applications

Unspecified application

Species

Unspecified reactive species

Michelle Joy-Immediato,Manuel J Ramirez,Mauricio Cerda,Yusuke Toyama,Andrea Ravasio,Pakorn Kanchanawong,Cristina Bertocchi
View all publications
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Product promise

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