AM 80, retinoic acid receptor alpha/beta (RAR alpha/beta) agonist

Key facts

CAS number

94497-51-5

Purity

>98%

Form

Solid

form

Molecular weight

351.44 g/mol

Molecular formula

C₂₂H₂₅NO₃

Nature

Synthetic

Solubility

Soluble in 1.1 eq NaOH to 100 mM

Soluble in DMSO to 50 mM

Biological description

Selective retinoic acid receptor α/β (RARα/β) agonist. Induces differentiation and anti-cancer activity in vivo and in vitro.

Canonical smiles

O=C(O)C1CCC(CC1)C(=O)NC2CCC3C(C2)C(C)(C)CCC3(C)C

InChi

InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-16(9-10-17(18)21)23-19(24)14-5-7-15(8-6-14)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)

InChiKey

MUTNCGKQJGXKEM-UHFFFAOYSA-N

IUPAC Name

4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid