Aminopurvalanol A, cyclin-dependent kinase inhibitor
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MW 403.9 Da, Purity >99%. Potent, cell-permeable cyclin-dependent kinase inhibitor (IC50 values are 33 (cdk1/cyclin B), 33 (cdk2/cyclin A), 28 (cdk2/cyclin E) and 20 nM (cdk5/p35)). Inhibits ERK1 (IC50 = 12.0 μM) and ERK2 (IC50 = 3.1 μM). Induces cell cycle arrest at G2/M phase (IC50 = 1.25 μM). Shows apoptotic effects.
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(R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, 1,8-cineole 2-exo-monooxygenase, AI838772, AW493413, Albendazole monooxygenase, Albendazole sulfoxidase, CCNB, CCNB1_HUMAN, CCNB2_HUMAN, CDC-like kinase 1, CDC28/CDC2 like kinase, CDC28A, CDK1_HUMAN, CDKN1, CELL CYCLE CONTROLLER CDC2, CLK/STY, CLK1_HUMAN, CP2C9_HUMAN, CP33, CP34, CP3A4_HUMAN, CPC9, CYP2C, CYP2C10, CYP3, CYP3A, CYP3A3, CYP3A4, CYPIIC9, CYPIIIA3, CYPIIIA4, Cdc 2, Cell Divsion Cycle 2 Protein, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, Cell division protein kinase 1, CycB2, Cyclin B1, Cyclin B2, Cyclin-dependent kinase 1, Cytochrome P-450MP, Cytochrome P450 2C9, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome P450 MP-4, Cytochrome P450 MP-8, Cytochrome P450 NF-25, Cytochrome P450 PB-1, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 subfamily IIIA polypeptide 4, Cytochrome P450, family 2, subfamily C, polypeptide 9, Cytochrome P450-PCN1, DKFZp686L20222, Dual specificity protein kinase CLK1, FLJ11090, G2 mitotic specific cyclin B1, G2 mitotic specific cyclin B2, G2/mitotic specific cyclin B3, G2/mitotic-specific cyclin-B1, G2/mitotic-specific cyclin-B2, Glucocorticoid inducible P450, HLP, HsT17299, MGC104252, MGC108931, MGC111195, MGC112732, MGC126680, MGC140694, MGC149605, MGC88320, Microsomal monooxygenase, NF 25, Nifedipine oxidase, OTTHUMP00000020135, P34CDC2, P450 III steroid inducible, P450 MP, P450 PB 1, P450 PCN1, P450, family III, P450C3, P450IIC9, Protein tyrosine kinase STY, Quinine 3-monooxygenase, RP11 805H4.3, RP24-311F12.2, S-mephenytoin 4-hydroxylase, SCAN1, STY, TYDP, TYDP1_HUMAN, Taurochenodeoxycholate 6-alpha-hydroxylase, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, Xenobiotic monooxygenase, cytochrome P-450 S-mephenytoin 4-hydroxylase, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, flavoprotein-linked monooxygenase, p34 Cdk1, p34 protein kinase
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Chemical Structure - Aminopurvalanol A, cyclin-dependent kinase inhibitor (AB145052)
2D chemical structure image of ab145052, Aminopurvalanol A, cyclin-dependent kinase inhibitor
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