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MW 270.24 Da, Purity >98%. Plant flavone. Antioxidant, anti-inflammatory and anticancer properties. Effects a wide range of molecular targets including caspases, fatty acid synthase, topoisomerase and nuclear factor-κB.

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Images

Chemical Structure - Apigenin, Anticancer agent (AB120141), expandable thumbnail
  • Functional Studies - Apigenin, Anticancer agent (AB120141), expandable thumbnail

Publications

Key facts

CAS number
520-36-5
Purity
> 98%
Form
Solid
Molecular weight
270.24 Da
Molecular formula
C15H10O5
PubChem identifier
5280443
Nature
Synthetic

Target data

Recommended products

MW 270.24 Da, Purity >98%. Plant flavone. Antioxidant, anti-inflammatory and anticancer properties. Effects a wide range of molecular targets including caspases, fatty acid synthase, topoisomerase and nuclear factor-κB.

Key facts

Purity
> 98%
PubChem identifier
5280443
Solubility

Soluble in DMSO to 100 mM.

Biochemical name
Apigenin
Biological description

Plant flavone. Antioxidant, anti-inflammatory and anticancer properties. Effects a wide range of molecular targets including caspases, fatty acid synthase, topoisomerase and nuclear factor-κB.

Canonical SMILES
C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
InChI
InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
InChIKey
KZNIFHPLKGYRTM-UHFFFAOYSA-N
IUPAC name
5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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2 product images

  • Chemical Structure - Apigenin, Anticancer agent (ab120141), expandable thumbnail

    Chemical Structure - Apigenin, Anticancer agent (ab120141)

    2D chemical structure image of ab120141, Apigenin, Anticancer agent

  • Functional Studies - Apigenin, Anticancer agent (ab120141), expandable thumbnail
    Bauer et al PLoS One. 2017 Apr 25;12(4):e0175558. doi: 10.1371/journal.pone.0175558. eCollection 2017. Fig 2. Reproduced under the Creative Commons license https://creativecommons.org/publicdomain/zero/1.0/

    Functional Studies - Apigenin, Anticancer agent (ab120141)

    (A-D). The release of cytokines as assessed using Human Cytokine Array C1000 membranes from MDA-MB-231 cells ± TNFα ± Apigenin. [A] Ctrls, [B] TNFα-treated (40ng/mL) [C] Apigenin (40μM) and [D] TNFα-treated (40ng/mL) + Apigenin (40μM) co-treated cells.

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