Apoptosis Activator 2 (AAII), Cytochrome c caspase activator and apoptosis inducer

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MW 306.1 Da, Purity >99%. Cell-permeable cytochrome c caspase activator. Promoting cytochrome-c dependent oligomerization of Apaf-1 into the mature apoptosome. Induces apoptosis in tumor cells (IC₅₀ = ~4 μM).

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15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE, 15 LO 2, 15 LOX 1, 15 lipoxygenase 1, 15-LOX, 15-LOX-2, 15-LOX-B, 15-lipoxygenase 2, A830040C14Rik, ACAT, ACEE, ACES_HUMAN, AHDC, AI413597, AI838772, ALDC, ALDH 1, ALDH 11, ALDH class 1, ALDH class 2, ALDH-E1, ALDH-E2, ALDHI, ALDM, ALHDII, ALOX15, APAF-3, APAF_HUMAN, APOPAIN, ARACHE, AW045860, AW493413, Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase 2, Acetylcholinesterase, Acyl coenzyme A cholesterol acyltransferase, Acyl-coenzyme A:cholesterol acyltransferase, Acylcholine acylhydrolase, Aldehyde dehydrogenase 1, Aldehyde dehydrogenase 1 family member A1, Aldehyde dehydrogenase 1 soluble, Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase 2 family, Aldehyde dehydrogenase 2 family (mitochondrial), Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase liver cytosolic, Aldehyde dehydrogenase mitochondrial, Aldh, Alox15b, Antigen NY-CO-13, Apoptosis related acetylcholinesterase, Apoptosis related cysteine peptidase, Apoptotic peptidase activating factor 1, Apoptotic protease Mch-6, Apoptotic protease activating factor, Apoptotic protease-activating factor 1, Apoptotic protease-activating factor 3, Arachidonate 15 lipoxygenase second type, Arachidonate 15-lipoxygenase, Arachidonate 15-lipoxygenase B, Arachidonate 15-lipoxygenase type II, Arachidonate omega-6 lipoxygenase, BCC7, BCHE, Brain carboxylesterase hBr1, Butyrylcholine esterase, CASP3_HUMAN, CASP9_HUMAN, CC3, CE 1, CED 4, CEH, CES2, CESDD1, CHE 1, CHE2, CHLE_HUMAN, CP2D6_HUMAN, CPD6, CPP-32, CPP32B, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, Carboxyesterase ES-3, Carboxylesterase, Carboxylesterase 1, Carboxylesterase 1 (monocyte/macrophage serine esterase 1), Carboxylesterase 1 deficiency, included, Carboxylesterase 2, formerly, Casp3a, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase 9 Dominant Negative, Caspase 9 apoptosis related cysteine peptidase, Caspase 9c, Caspase-3, Caspase-3 subunit p12, Caspase-9, Caspase-9 subunit p10, Cellular tumor antigen p53, Ces-1, Cholesterol 25-hydroxylase, Cholesterol ester hydrolase, neutral, macrophage-derived, Cholesteryl ester hydrolase, Choline esterase II, Cholinesterase, Cholinesterase (serum) 2, Cholinesterase 1, Cocaine carboxylesterase, Cysteine protease CPP32, Cytochrome P450 2D6, Cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 family 2 subfamily D polypeptide 6, Cytochrome P450-DB1, DDPAC, Debrisoquine 4-hydroxylase, E1, EC 3.1.1.1, EC 3.4.22.56, ES-HTEL, ES-x, EST1_HUMAN, Egasyn, Es22, Esterase, Esterase 22, FLJ11090, FLJ31424, FLJ92943, FTDP 17, G protein beta1/gamma2 subunit interacting factor 1, HMSE, HMSE1, ICE-LAP6, ICE-like apoptotic protease 6, ICE3, KIAA0413, LFS1, LICE, LOG15, LOX15_HUMAN, LX15B_HUMAN, Liver carboxylesterase 1, Liver carboxylesterase 3, Liver mitochondrial ALDH, MAPT, MAPTL, MCH6, MGC104252, MGC112732, MGC117365, MGC134287, MGC138549, MGC156521, MGC156663, MGC1806, MGC2318, MSTD, MTBT1, MTBT2, Methylumbelliferyl acetate deacetylase 1, Microsomal monooxygenase, Microtubule associated protein tau isoform 4, Microtubule-associated protein tau, Mitochondrial aldehyde dehydrogenase 2, Monocyte carboxylesterase deficiency, included, Monocyte esterase deficiency, included, Monocyte/macrophage serine esterase, Mtapt, Mutant tumor protein 53, N-ACHE, Neurofibrillary tangle protein, Nucleus encoded mitochondrial aldehyde dehydrogenase 2, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, P450 DB1, P450C2D, P53_HUMAN, PARP cleavage protease, PCE-1, PHF-tau, PPND, PPP1R103, PPP1R56, PUMB 1, Paired helical filament-tau, Phosphoprotein p53, Procaspase3, Proline-beta-naphthylamidase, Protein Yama, Protein phosphatase 1, regulatory subunit 103, Pseudocholinesterase, Pseudocholinesterase E1, RALDH 1, REH, RNCASP9, RNPTAU, RP24-311F12.2, Retinal dehydrogenase 1, Retinaldehyde dehydrogenase 1, Retinyl ester hydrolase, SCA-1, SCAN1, SREBP cleavage activity 1, Serine esterase 1, Ses-1, TAU_HUMAN, TGH, TRP53, TYDP, TYDP1_HUMAN, Tauopathy and respiratory failure, Tauopathy and respiratory failure, included, Tp53, Transformation related protein 53, Triacylglycerol hydrolase, Tumor protein 53, Tumor protein p53, Tumor suppressor p53, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, Xenobiotic monooxygenase, YT, YT blood group, Yama, Yama protein, flavoprotein-linked monooxygenase, hCE 1, mldy, p53 tumor suppressor, pI 5.5 esterase, pTau, protein phosphatase 1, regulatory subunit 56, tumor antigen p55