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AB120916

Arachidonic acid, omega-6 Polyunsaturated fatty acid

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(5 Publications)

MW 304.47 g/mol, Purity >98%. Major precursor in the production of eicosanoids and important cellular signaling mediator. Endogenous free fatty acid released from phospholipids by PLA2. Metabolised by COX, lipoxygenase and cytochrome p450s to form a variety of eicosanoids including PGs and LTs.
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Chemical Structure - Arachidonic acid, omega-6 Polyunsaturated fatty acid (AB120916)
  • Chemical Structure

Lab

Chemical Structure - Arachidonic acid, omega-6 Polyunsaturated fatty acid (AB120916)

2D chemical structure image of ab120916, Arachidonic acid, omega-6 Polyunsaturated fatty acid

Key facts

CAS number

506-32-1

Purity

>98%

Form

Liquid

form

Molecular weight

304.47 g/mol

Molecular formula

C<sub>2</sub><sub>0</sub>H<sub>3</sub><sub>2</sub>O<sub>2</sub>

Nature

Synthetic

Biological description

Major precursor in the production of eicosanoids and important cellular signaling mediator. Endogenous free fatty acid released from phospholipids by PLA2. Metabolised by COX, lipoxygenase and cytochrome p450s to form a variety of eicosanoids including PGs and LTs.

Isomeric smiles

CCCCC/C=CC/C=CC/C=CC/C=CCCCC(=O)O

IUPAC Name

5Z,8Z,11Z,14Z-Eicosatetraenoic acid

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions

Product protocols

Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Lipids in health and disease 24:44 PubMed39934848

2025

Arachidonic acid is involved in high-salt diet-induced coronary remodeling through stimulation of the IRE1α/XBP1s/RUNX2/OPN signaling cascade.

Applications

Unspecified application

Species

Unspecified reactive species

Zhuoran Jia,Jian Wu,Fang Liu,Huimin Wang,Peiyang Zheng,Bing Shen,Ren Zhao

International journal of molecular sciences 24: PubMed37958498

2023

Targeted Mass Spectrometry Reveals Interferon-Dependent Eicosanoid and Fatty Acid Alterations in Chronic Myeloid Leukaemia.

Applications

Unspecified application

Species

Unspecified reactive species

Hannah C Scott,Simeon D Draganov,Zhanru Yu,Benedikt M Kessler,Adán Pinto-Fernández

Nature communications 12:907 PubMed33568645

2021

Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Zhongde Ye,Yi Shen,Ke Jin,Jingtao Qiu,Bin Hu,Rohit R Jadhav,Khushboo Sheth,Cornelia M Weyand,Jörg J Goronzy

International journal of molecular sciences 21: PubMed32392840

2020

Arachidonic Acid Attenuates Cell Proliferation, Migration and Viability by a Mechanism Independent on Calcium Entry.

Applications

Unspecified application

Species

Unspecified reactive species

Carlos Cantonero,Jose Sánchez-Collado,Jose J Lopez,Ginés M Salido,Juan A Rosado,Pedro C Redondo

Frontiers in immunology 9:456 PubMed29563916

2018

Old Yellow Enzyme from Exhibits Prostaglandin Fα Synthase Activity and Has a Key Role in Parasite Infection and Drug Susceptibility.

Applications

Unspecified application

Species

Unspecified reactive species

Florencia Díaz-Viraqué,María Laura Chiribao,Andrea Trochine,Fabiola González-Herrera,Christian Castillo,Ana Liempi,Ulrike Kemmerling,Juan Diego Maya,Carlos Robello
View all publications

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