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MW 384.4 Da, Purity >98%. Semi-synthetic artemisinin (Asc-1308) derivative. Induces apoptosis of vascular endothelial cells. Shows antiangiogenenic and antiparasitaemic effects in vivo. Orally active.

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Images

Chemical Structure - Artesunate, artemisinin derivative (AB142829), expandable thumbnail

Key facts

CAS number
182824-33-5
Purity
> 98%
Form
Solid
Source
Artemisia annua
Molecular weight
384.4 Da
Molecular formula
C19H28O8
PubChem identifier
65664
Nature
Native

Target data

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MW 384.4 Da, Purity >98%. Semi-synthetic artemisinin (Asc-1308) derivative. Induces apoptosis of vascular endothelial cells. Shows antiangiogenenic and antiparasitaemic effects in vivo. Orally active.

Key facts

Purity
> 98%
Source
Artemisia annua
PubChem identifier
65664
Solubility

Soluble in ethanol to 50 mM.

Soluble in DMSO to 50 mM.

Biochemical name
beta-Artesunate
Biological description

Semi-synthetic artemisinin (Asc-1308) derivative. Induces apoptosis of vascular endothelial cells. Shows antiangiogenenic and antiparasitaemic effects in vivo. Orally active.

Canonical SMILES
CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C
Isomeric SMILES
C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC(=O)CCC(=O)O)C
InChI
InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18-,19-/m1/s1
InChIKey
FIHJKUPKCHIPAT-NKHDUEHSSA-N
IUPAC name
4-oxo-4-[[(1R,4S,5R,8S,9R,10R,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - Artesunate, artemisinin derivative (ab142829), expandable thumbnail

    Chemical Structure - Artesunate, artemisinin derivative (ab142829)

    2D chemical structure image of ab142829, Artesunate, artemisinin derivative

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Product protocols

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