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AB120898

AS-041164, PI3K gamma inhibitor

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MW 249.24 g/mol, Purity >98%. Potent PI3K inhibitor with selectivity for PI3Kγ (IC50 = 70 nM), compared to PI3Kα, β and δ (IC50 values are 240 nM, 1.45 and 1.70 μM, respectively). Shows little or n o activity against 38 other common kinases. Blocks neutrophil migration. Active in vivo.
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Chemical Structure - AS-041164, PI3K gamma inhibitor (AB120898)
  • Chemical Structure

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Chemical Structure - AS-041164, PI3K gamma inhibitor (AB120898)

2D chemical structure image of ab120898, AS-041164, PI3K gamma inhibitor

Key facts

CAS number

6318-41-8

Purity

>98%

Molecular weight

249.24 g/mol

Molecular formula

C<sub>1</sub><sub>1</sub>H<sub>7</sub>NO<sub>4</sub>S

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biological description

Potent PI3K inhibitor with selectivity for PI3Kγ (IC50 = 70 nM), compared to PI3Kα, β and δ (IC50 values are 240 nM, 1.45 and 1.70 μM, respectively). Shows little or n o activity against 38 other common kinases. Blocks neutrophil migration. Active in vivo.

Isomeric smiles

O=C(/C(S1)=C/C2=CC=C3C(OCO3)=C2)NC1=O

IUPAC Name

5-[(1,3-Benzodioxol-5-yl)methylene]-2,4-thiazolidinedione

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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