Atorvastatin hemicalcium salt, HMG-CoA reductase inhibitor

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MW 1155.3 Da, Purity >99%. Potent HMG-CoA reductase inhibitor (IC₅₀ = 8 nM). Metabolised by CYP3A4. Able to reduce circulating LDL-C through inhibition of cholesterol biosynthesis and inducing expression of LDL receptors.

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3 hydroxy 3 methylglutaryl CoA reductase, 3 hydroxymethylglutaryl CoA reductase, 3-hydroxy-3-methylglutaryl CoA reductase (NADPH), 3-hydroxy-3-methylglutaryl-coenzyme A reductase, 3H3M, A830040C14Rik, ABC 31, ABC member 16, MDR/TAP subfamily, ABC16, ABCB1, ABCBB_HUMAN, ABCC 3, AI838772, APOPAIN, ATP binding cassette sub family B (MDR/TAP) member 11, ATP binding cassette sub family C (CFTR/MRP) member 3, ATP-binding cassette sub-family B member 11, ATP-binding cassette sub-family C member 3, AW493413, Apoptotic protease Mch-3, Atherosclerosis, susceptibility to, included, BRIC2, BXR, Bile salt export pump, Bsep, CASP3_HUMAN, CASP7_HUMAN, CC3, CMH-1, CMOAT 2, CPP-32, CPP32B, Canalicular multispecific organic anion transporter 2, Canicular multispecific organic anion transporter, Casp3a, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase 7, Caspase 7 apoptosis related cysteine peptidase, Caspase-3, Caspase-3 subunit p12, Caspase-7 subunit p11, Cysteine protease CPP32, DKFZp686N23123, EC 3.4.22.56, ER, ER-alpha, ER-beta, ERR a, ERR-alpha, ERR1 protein, ERR1_HUMAN, ER[a], ER[b], ESR, ESR B, ESR BETA, ESR1_HUMAN, ESRA, ESRL 1, ESRR A, EST90757, ESTR B, Era, Erb, Erb2, Estr, Estra, Estradiol Receptor alpha, Estradiol Receptor beta, Estradiol receptor, Estrogen Receptor 1, Estrogen Receptor 2, Estrogen receptor, Estrogen receptor 1 (alpha), Estrogen receptor 2 (ER beta), Estrogen receptor 2 ER beta, Estrogen receptor alpha, Estrogen receptor beta 4, Estrogen receptor related 1, Estrogen receptor-like 1, Estrogen resistance, included, Estrogen-related receptor alpha, Estrra, FLJ11090, GCCR, GCRST, GCR_HUMAN, GR, Glucocorticoid receptor, Grl1, HDL cholesterol, augmented response of, to hormone replacement, included, HMDH_HUMAN, HMG CoAR, HMG-CoA reductase, Hydroxymethylglutaryl CoA reductase, ICE-LAP3, ICE-like apoptotic protease 3, ICE3, IMD42, LDLCQ3, LICE, LICE2, Liver-specific organic anion transporter 1, MCH3, MGC103269, MGC104252, MGC112732, MGC129539, MLP 2, MOAT-D, MRP3_HUMAN, Multi-specific organic anion transporter D, Multidrug resistance associated protein, Multidrug resistance-associated protein 3, Multispecific organic anion tranporter D, Myocardial infarction, susceptibility to, included, NF-E2-related factor 2, NF2L2_HUMAN, NR1F3, NR1I2_HUMAN, NR3A1, NR3A2, NR3B1, NRF2, Nfe2l2, Nuclear factor, Nuclear factor (erythroid derived 2) like 2, Nuclear factor erythroid 2-related factor 2, Nuclear factor erythroid derived 2 like 2, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, Nuclear receptor subfamily 1 group I member 2, Nuclear receptor subfamily 3 group A member 1, Nuclear receptor subfamily 3 group A member 2, Nuclear receptor subfamily 3 group B member 1, Nuclear receptor subfamily 3 group C member 1, OATP-2, OATP-C, ONR 1, OTTHUMP00000017718, OTTHUMP00000017719, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, OTTHUMP00000215173, OTTHUMP00000215174, OTTHUMP00000215175, Orphan nuclear receptor PAR 1, Orphan nuclear receptor PXR, PAR, PAR q, PARP cleavage protease, PFIC 2, PGY4, PRR, Pregnane X receptor, Procaspase3, Protein Yama, RAR related orphan nuclear receptor variant 2, RAR related orphan receptor C, isoform a, RAR related orphan receptor gamma, RAR-related orphan receptor C, RNESTROR, RORG_HUMAN, RP24-311F12.2, RZR GAMMA, RZRG, Retinoic acid binding receptor gamma, Retinoid-related orphan receptor-gamma, Rorc, SCA-1, SCAN1, SLC21A6, SLCO1B1, SO1B1_HUMAN, SREBP cleavage activity 1, SXR, Sister of P glycoprotein, Sodium-independent organic anion-transporting polypeptide 2, Solute carrier family 21 member 6, Solute carrier organic anion transporter family member 1B1, Spgp, Steroid and xenobiotic receptor, Steroid hormone receptor ERR1, TOR, TYDP, TYDP1_HUMAN, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, Yama, Yama protein, erythroid derived 2, estrogen receptor related receptor alpha, glucocorticoid nuclear receptor variant 1, hERR1, like 2, mldy, nr3c1, nuclear factor erythroid 2 like 2, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), pregnane X nuclear receptor variant 2, progressive familial intrahepatic cholestasis 2