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AB141907

Auraptene, Activates PPARalpha and PPARgamma

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MW 298.4 Da, Purity >98%. Activates PPARα and PPARγ. Inhibits acyl-CoA:cholesterol acyl transferase (ACAT). Modulates estrogen receptors and disrupts ERK1/2-mediated phosphorylation of 4EBP1 and eIF4B. Chemopreventive properties. Active in vivo and in vitro.

View Alternative Names

MEL-1A-R, MR, MT-1, MTNR 1A, MTR1A_HUMAN, Mel1a melatonin receptor, Mel1a receptor, MelR, Melatonin receptor 1A, Melatonin receptor type 1A

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Chemical Structure - Auraptene, Activates PPARalpha and PPARgamma (AB141907)
  • Chemical Structure

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Chemical Structure - Auraptene, Activates PPARalpha and PPARgamma (AB141907)

2D chemical structure image of ab141907, Auraptene, Activates PPARalpha and PPARgamma

Key facts

CAS number

495-02-3

Purity

>98%

Source

Citrus sp.

Molecular weight

298.4 Da

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>2</sub><sub>2</sub>O<sub>3</sub>

PubChem

1550607

Nature

Native

Solubility

Soluble in DMSO to 50 mM

Biochemical name

Auraptene

Biological description

Activates PPARα and PPARγ. Inhibits acyl-CoA:cholesterol acyl transferase (ACAT). Modulates estrogen receptors and disrupts ERK1/2-mediated phosphorylation of 4EBP1 and eIF4B. Chemopreventive properties. Active in vivo and in vitro.

Canonical smiles

CC(=CCCC(=CCOC1=CC2=C(C=C1)C=CC(=O)O2)C)C

Isomeric smiles

CC(=CCC/C(=C/COC1=CC2=C(C=C1)C=CC(=O)O2)/C)C

InChi

InChI=1S/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+

InChiKey

RSDDHGSKLOSQFK-RVDMUPIBSA-N

IUPAC Name

7-[(2E)-3,7-dimethylocta-2,6-dienoxy]chromen-2-one

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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