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MW 298.4 Da, Purity >98%. Activates PPARα and PPARγ. Inhibits acyl-CoA:cholesterol acyl transferase (ACAT). Modulates estrogen receptors and disrupts ERK1/2-mediated phosphorylation of 4EBP1 and eIF4B. Chemopreventive properties. Active in vivo and in vitro.

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Images

Chemical Structure - Auraptene, Activates PPARalpha and PPARgamma (AB141907), expandable thumbnail

Key facts

CAS number
495-02-3
Purity
> 98%
Source
Citrus sp.
Molecular weight
298.4 Da
Molecular formula
C19H22O3
PubChem identifier
1550607
Nature
Native

Target data

Alternative names

MEL-1A-R, MR, MT-1, MTNR 1A, MTR1A_HUMAN, Mel1a melatonin receptor, Mel1a receptor, MelR, Melatonin receptor 1A, Melatonin receptor type 1A

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MW 298.4 Da, Purity >98%. Activates PPARα and PPARγ. Inhibits acyl-CoA:cholesterol acyl transferase (ACAT). Modulates estrogen receptors and disrupts ERK1/2-mediated phosphorylation of 4EBP1 and eIF4B. Chemopreventive properties. Active in vivo and in vitro.

Key facts

Purity
> 98%
Source
Citrus sp.
PubChem identifier
1550607
Solubility

Soluble in DMSO to 50 mM.

Biochemical name
Auraptene
Biological description

Activates PPARα and PPARγ. Inhibits acyl-CoA:cholesterol acyl transferase (ACAT). Modulates estrogen receptors and disrupts ERK1/2-mediated phosphorylation of 4EBP1 and eIF4B. Chemopreventive properties. Active in vivo and in vitro.

Canonical SMILES
CC(=CCCC(=CCOC1=CC2=C(C=C1)C=CC(=O)O2)C)C
Isomeric SMILES
CC(=CCC/C(=C/COC1=CC2=C(C=C1)C=CC(=O)O2)/C)C
InChI
InChI=1S/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+
InChIKey
RSDDHGSKLOSQFK-RVDMUPIBSA-N
IUPAC name
7-[(2E)-3,7-dimethylocta-2,6-dienoxy]chromen-2-one

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - Auraptene, Activates PPARalpha and PPARgamma (ab141907), expandable thumbnail

    Chemical Structure - Auraptene, Activates PPARalpha and PPARgamma (ab141907)

    2D chemical structure image of ab141907, Auraptene, Activates PPARalpha and PPARgamma

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Product protocols

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