Skip to main content

MW 270.24 g/mol, Purity >98%. Cell-permeable flavonoid. Lipoxygenase inhibitor (IC50 values are 0.64 and 1.6 μM at 12- and 15-lipoxygenases, respectively). Shows antioxidant and anti-inflammatory properties. Also induces apoptosis. Additionally, inhibits α-syn oligomerisation, β-Amyloid induced neurotoxicity and amyloid protein aggregation.

Be the first to review this product! Submit a review

Images

Key facts

CAS number

491-67-8

Purity

> 98%

Form

Solid

Molecular weight

270.24 g/mol

Molecular formula

C15H10O5

Nature

Synthetic

Loading...
Loading...
Loading...
Loading...
Loading...
Loading...
Loading...
Loading...

Recommended products

  1. Loading...
  2. Loading...
  3. Loading...
  4. Loading...

MW 270.24 g/mol, Purity >98%. Cell-permeable flavonoid. Lipoxygenase inhibitor (IC50 values are 0.64 and 1.6 μM at 12- and 15-lipoxygenases, respectively). Shows antioxidant and anti-inflammatory properties. Also induces apoptosis. Additionally, inhibits α-syn oligomerisation, β-Amyloid induced neurotoxicity and amyloid protein aggregation.

Key facts

Purity

> 98%

Biological description

Cell-permeable flavonoid. Lipoxygenase inhibitor (IC50 values are 0.64 and 1.6 μM at 12- and 15-lipoxygenases, respectively). Shows antioxidant and anti-inflammatory properties. Also induces apoptosis. Additionally, inhibits α-syn oligomerisation, β-Amyloid induced neurotoxicity and amyloid protein aggregation.

IUPAC name

5,6,7-Trihydroxy-2-phenyl-(4H)-1-benzopyran-4-one

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate long-term storage conditions

-20°C

Storage information

Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

2 product images

  • Chemical Structure - Baicalein, Lipoxygenase inhibitor. (ab120723), expandable thumbnail

    Chemical Structure - Baicalein, Lipoxygenase inhibitor. (ab120723)

    2D chemical structure image of ab120723, Baicalein, Lipoxygenase inhibitor.

  • Immunocytochemistry/ Immunofluorescence - Baicalein, Lipoxygenase inhibitor. (ab120723), expandable thumbnail

    Immunocytochemistry/ Immunofluorescence - Baicalein, Lipoxygenase inhibitor. (ab120723)

    ab51608 staining HIF1α in HepG2 cells treated with baicalein (ab120723), by ICC/IF. Increase in HIF1α expression correlates with increased concentration of baicalein as described in literature.
    The cells were incubated at 37°C for 6h in media containing different concentrations of ab120723 (baicalein) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab51608 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody.

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

There was a problem

We can’t download that datasheet. Please try again. If you need help, contact our Customer Services team at technical@abcam.com