BAPTA tetrasodium salt, Ca2+chelator

Key facts

CAS number

126824-24-6

Purity

>95%

Form

Solid

form

Molecular weight

564.4 Da

Molecular formula

C₂₂H₂₀N₂Na₄O₁₀

PubChem

2734965

Nature

Synthetic

Solubility

Soluble in water to 50 mM

Biochemical name

Sodium 2,2',2'',2'''-(((ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis(azanetriyl))tetraacetate

Biological description

Selective Ca2+ chelator. Useful for measurement and manipulation of intracellular free Ca2+levels. Also displays potent actin and microtubule depolymerizing activity independent of Ca2+ chelation.

Canonical smiles

C1=CC=C(C(=C1)N(CC(=O)[O-])CC(=O)[O-])OCCOC2=CC=CC=C2N(CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Na+].[Na+]

InChi

InChI=1S/C22H24N2O10.4Na/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32;;;;/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32);;;;/q;4*+1/p-4

InChiKey

ZWSMLJACYSGFKD-UHFFFAOYSA-J

IUPAC Name

tetrasodium;2-[2-[2-[2-[bis(carboxylatomethyl)amino]phenoxy]ethoxy]-N-(carboxylatomethyl)anilino]acetate